Evidence map›Paper›PMID 36061360›Full record

ArticleDisease markers2022

UHPLC-MS/MS-Based Metabolomics and Clinical Phenotypes Analysis Reveal Broad-Scale Perturbations in Early Pregnancy Related to Gestational Diabetes Mellitus.

Ting Hu, Zhuoling An, Han Li, Yanping Liu, Liangyu Xia, Ling Qiu, Aimin Yao, Liangkun Ma, Lihong Liu

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ting HuBeijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.ORCID https://orcid.org/0000-0002-0538-0300
Zhuoling AnBeijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.
Han LiBeijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.
Yanping LiuPeking Union Medical College Hospital, China Academic Medical Science and Peking Union Medical College, Beijing 100730, China.
Liangyu XiaPeking Union Medical College Hospital, China Academic Medical Science and Peking Union Medical College, Beijing 100730, China.
Ling QiuPeking Union Medical College Hospital, China Academic Medical Science and Peking Union Medical College, Beijing 100730, China.
Aimin YaoShunyi District Maternal and Child Health Hospital, Beijing 101320, China.
Liangkun MaPeking Union Medical College Hospital, China Academic Medical Science and Peking Union Medical College, Beijing 100730, China.ORCID https://orcid.org/0000-0001-5758-0198
Lihong LiuBeijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.ORCID https://orcid.org/0000-0002-1203-596X
Capital Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNShunyi Hospital of Beijing Traditional Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is the most common metabolic disturbance during pregnancy, with adverse effects on both mother and fetus. The establishment of early diagnosis and risk assessment model is of great significance for preventing and reducing adverse outcomes of GDM. In this study, the broad-scale perturbations related to GDM were explored through the integration analysis of metabolic and clinical phenotypes. Maternal serum samples from the first trimester were collected for targeted metabolomics analysis by using ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). Statistical analysis was conducted based on the levels of the 184 metabolites and 76 clinical indicators from GDM women (

Indexed as

Diabetes, GestationalChromatography, High Pressure LiquidFemaleHumansMetabolomicsPhenotypePregnancyTandem Mass SpectrometryUric AcidUric Acid

Identifiers

PMID36061360
PMCPMC9433254
OpenAlexW4293213159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.