Evidence map›Paper›PMID 36061221›Full record

ReviewGEN biotechnology2022

Deep Learning Concepts and Applications for Synthetic Biology.

William A V Beardall, Guy-Bart Stan, Mary J Dunlop

Abstract readReview
In one paragraph

Review in GEN biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Design biology and mind-body health.Journal, genetic engineering & biotechnology · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Data hazards in synthetic biology.Synthetic biology (Oxford, England) · 2024
    Review
  10. Review
  11. Opportunities for engineering outer membrane vesicles using synthetic biology approaches.Extracellular vesicles and circulating nucleic acids · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William A V BeardallDepartment of Bioengineering, Imperial College London, London, United Kingdom.
Guy-Bart StanDepartment of Bioengineering, Imperial College London, London, United Kingdom.
Mary J DunlopDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-9261-8216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic biology has a natural synergy with deep learning. It can be used to generate large data sets to train models, for example by using DNA synthesis, and deep learning models can be used to inform design, such as by generating novel parts or suggesting optimal experiments to conduct. Recently, research at the interface of engineering biology and deep learning has highlighted this potential through successes including the design of novel biological parts, protein structure prediction, automated analysis of microscopy data, optimal experimental design, and biomolecular implementations of artificial neural networks. In this review, we present an overview of synthetic biology-relevant classes of data and deep learning architectures. We also highlight emerging studies in synthetic biology that capitalize on deep learning to enable novel understanding and design, and discuss challenges and future opportunities in this space.

Identifiers

PMID36061221
PMCPMC9428732

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.