Evidence map›Paper›PMID 36060813›Full record

ArticleFrontiers in cell and developmental biology2022

Proteasomal subunit depletions differentially affect germline integrity in

Lourds Michelle Fernando, Cristina Quesada-Candela, Makaelah Murray, Caroline Ugoaru, Judith L Yanowitz, Anna K Allen

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Active maintenance of meiosis-specific chromosome structures inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Active maintenance of meiosis-specific chromosome structures inbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Cells · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lourds Michelle FernandoDepartment of Biology, Howard University, Washington, DC, United States.
Cristina Quesada-CandelaMagee-Womens Research Institute and Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Makaelah MurrayDepartment of Biology, Howard University, Washington, DC, United States.
Caroline UgoaruDepartment of Biology, Howard University, Washington, DC, United States.
Judith L YanowitzMagee-Womens Research Institute and Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Anna K AllenDepartment of Biology, Howard University, Washington, DC, United States.

Funding

Role of Chromosomally Tethered Proteasome in Chromosome Pairing and Meiotic RecombinationR01GM125800 · NIGMS · CLEVELAND STATE UNIVERSITY · PI BOERNER, VALENTIN · 2018 to 2021
$2.3M
COELOMOCYTES IN C.ELEGANS--CELL FATE DETERMINATIONF32HD008715 · NICHD · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI YANOWITZ, JUDITH L · 2000 to 2002
$112k
NICHD NIH HHS F32 HD008715NIGMS NIH HHS R01 GM125800
6 · The paper itself

Abstract

The 26S proteasome is a multi-subunit protein complex that is canonically known for its ability to degrade proteins in cells and maintain protein homeostasis. Non-canonical or non-proteolytic roles of proteasomal subunits exist but remain less well studied. We provide characterization of germline-specific functions of different 19S proteasome regulatory particle (RP) subunits in

Indexed as

19S regulatory particleC. elegansgerm linemeiosisproteasome

Identifiers

PMID36060813
PMCPMC9428126

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.