Evidence map›Paper›PMID 36060803›Full record

ArticleFrontiers in cell and developmental biology2022

Integrating single cell transcriptomics and volume electron microscopy confirms the presence of pancreatic acinar-like cells in sea urchins.

Periklis Paganos, Paolo Ronchi, Jil Carl, Giulia Mizzon, Pedro Martinez, Giovanna Benvenuto, Maria Ina Arnone

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Periklis PaganosStazione Zoologica Anton Dohrn (SZN), Naples, Italy.
Paolo RonchiEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Jil CarlEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Giulia MizzonEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Pedro MartinezInstitut Català de Recerca i Estudis Avancats (ICREA), Barcelona, Spain.
Giovanna BenvenutoStazione Zoologica Anton Dohrn (SZN), Naples, Italy.
Maria Ina ArnoneStazione Zoologica Anton Dohrn (SZN), Naples, Italy.
European Molecular Biology Laboratory · DEStazione Zoologica Anton Dohrn · ITInstitució Catalana de Recerca i Estudis Avançats · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identity and function of a given cell type relies on the differential expression of gene batteries that promote diverse phenotypes and functional specificities. Therefore, the identification of the molecular and morphological fingerprints of cell types across taxa is essential for untangling their evolution. Here we use a multidisciplinary approach to identify the molecular and morphological features of an exocrine, pancreas-like cell type harbored within the sea urchin larval gut. Using single cell transcriptomics, we identify various cell populations with a pancreatic-like molecular fingerprint that are enriched within the

Indexed as

acinar cellsevolution of cell typesmorphologypancreasSBEMscRNAseqsea urchin

Identifiers

PMID36060803
PMCPMC9437490
OpenAlexW4292336320

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.