Evidence map›Paper›PMID 36060790›Full record

ArticleMatrix biology plus2022

Integrin α3 negative podocytes: A gene expression study.

L H Frommherz, S B Sayar, Y Wang, L K Trefzer, Y He, J Leppert, P Eßer, C Has

Abstract read
In one paragraph

Article in Matrix biology plus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

L H FrommherzDepartment of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany.
S B SayarDepartment of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany.
Y WangDepartment of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany.
L K TrefzerDepartment of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany.
Y HeDepartment of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany.
J LeppertDepartment of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany.
P EßerDepartment of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany.
C HasDepartment of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrin α3β1 is a cell adhesion receptor widely expressed in epithelial cells. Pathogenic variants in the gene encoding the integrin α3 subunit

Indexed as

A3−, integrin alpha3 deficient cells AB8/13 is a conditionally immortalized podocyte cell line carrying a temperature-sensitive T antigen as transgene, in text and figures the abbreviation Podo was used for simplicityCRISPR/Cas9HK2, human kidney-2ILNEBILNEB, interstitial lung disease, nephrotic syndrome and epidermolysis bullosaIntegrin α3KidneyNephrotic syndromePodoA3−, integrin α3 negative podocytesPodocyteSkin blistering

Identifiers

PMID36060790
PMCPMC9429797

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.