Successful Palliative Radiotherapy for Malignant Cardiac Obstruction Caused by Gastric Cancer.

Gastric cancer is a common malignancy and some patients are diagnosed with an unresectable stage of advanced gastric cancer. Although palliative radiotherapy (RT) is effective for several symptoms in gastric cancer, the duration of efficacy is limited. We report a case where palliative RT significantly improved malignant cardiac obstruction caused by gastric cancer over a long period of time. A 78-year-old woman was referred to our hospital for anorexia and severe anemia. Esophagogastroduodenoscopy showed the giant gastric tumor in cardia and it was thought to be the cause of anemia. Biopsy revealed poorly differentiated adenocarcinoma; she was diagnosed with gastric cancer. Her clinical cancer staging was IV and she wished to receive palliative care. The malignant cardiac obstruction became severe, and to improve the obstruction, palliative RT was performed. The gastric tumor with a diameter of 4 cm was significantly reduced and the obstruction disappeared. For three years after RT, she had no obstruction symptom. The sensitivity of cells to radiation is proportional to the degree of differentiation. Palliative RT is effective for several symptoms in gastric cancer, and in our case, the duration of RT efficacy was long. Hence, RT may be useful when the histological type is poorly differentiated in gastric cancer.