Evidence map›Paper›PMID 36060251›Full record

ArticleFrontiers in molecular biosciences2022

Preparation of RNAs with non-canonical 5' ends using novel di- and trinucleotide reagents for co-transcriptional capping.

Anaïs Depaix, Ewa Grudzien-Nogalska, Bartlomiej Fedorczyk, Megerditch Kiledjian, Jacek Jemielity, Joanna Kowalska

Abstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Application of Mammalian Nudix Enzymes to Capped RNA Analysis.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Article
  10. Trinucleotide mRNA Cap AnalogueJournal of the American Chemical Society · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anaïs DepaixDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Warsaw, Poland.
Ewa Grudzien-NogalskaDepartment of Cell Biology and Neuroscience, Rutgers University, New York, NJ, United States.
Bartlomiej FedorczykCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Megerditch KiledjianDepartment of Cell Biology and Neuroscience, Rutgers University, New York, NJ, United States.
Jacek JemielityCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Joanna KowalskaDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Warsaw, Poland.

Funding

Eukaryotic RNA NAD+ capping and deNADingR01GM126488 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI KILEDJIAN, MEGERDITCH · 2018 to 2023
$2.4M
NIGMS NIH HHS R01 GM126488
6 · The paper itself

Abstract

Many eukaryotic and some bacterial RNAs are modified at the 5' end by the addition of cap structures. In addition to the classic 7-methylguanosine 5' cap in eukaryotic mRNA, several non-canonical caps have recently been identified, including NAD-linked, FAD-linked, and UDP-glucose-linked RNAs. However, studies of the biochemical properties of these caps are impaired by the limited access to

Indexed as

dinucleotideFADIn vitro transcriptionNADRNA captrinucleotideUDP-glucose

Identifiers

PMID36060251
PMCPMC9437278

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.