Evidence map›Paper›PMID 36060054›Full record

ArticleiScience2022

Optical control of the β

Reggie Bosma, Nicola C Dijon, Yang Zheng, Hannes Schihada, Niels J Hauwert, Shuang Shi, Marta Arimont, Rick Riemens, Hans Custers, Andrea van de Stolpe and 5 more

Abstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Structural Mechanism of an Efficacy Photoswitch Targeting the βAngewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Photo-clenbuterol: Optical Control of βJournal of medicinal chemistry · 2025
    Article
  7. Review
  8. Cardiac optogenetics: shining light on signaling pathways.Pflugers Archiv : European journal of physiology · 2023
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Reggie BosmaDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Nicola C DijonSchool of Life Sciences, The Medical School, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
Yang ZhengDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Hannes SchihadaSection of Receptor Biology & Signaling, Department of Physiology & Pharmacology, Karolinska Institutet, 17165 Stockholm, Sweden.
Niels J HauwertDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Shuang ShiDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Marta ArimontDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Rick RiemensDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Hans CustersDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Andrea van de StolpeDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Henry F VischerDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Maikel WijtmansDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.
Nicholas D HollidaySchool of Life Sciences, The Medical School, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
Diederik W D KusterAmsterdam UMC Location Vrije Universiteit Amsterdam, Physiology, De Boelelaan 1117, Amsterdam, the Netherlands.
Rob LeursDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute for Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we synthesized and evaluated new photoswitchable ligands for the beta-adrenergic receptors β

Indexed as

Biochemical engineeringBiochemical research methodPhotomedicine

Identifiers

PMID36060054
PMCPMC9436767

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.