Evidence map›Paper›PMID 36060051›Full record

ArticleiScience2022

Rapid, enantioselective and colorimetric detection of D-arginine.

Xianzhe Yu, Binjie Zhang, Cailing Fan, Qianqian Yan, Shenglin Wang, Hui Hu, Qinxi Dong, Gengyu Du, Yanan Gao, Chaoyuan Zeng

Abstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xianzhe YuKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.
Binjie ZhangKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.
Cailing FanKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.
Qianqian YanKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.
Shenglin WangKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.
Hui HuKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.
Qinxi DongKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.
Gengyu DuDepartment of Chemistry, University of Virginia, Charlottesville, VA 22904, USA.
Yanan GaoKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.
Chaoyuan ZengKey Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

D-amino acids are of biological significance yet are not clearly understood due to the lack of powerful analytical tools for their identification. Thus, the specific detection of a single enantiomer of a particular amino acid remains a great challenge due to their structural similarity. Here, we report a strategy to incorporate multiple reaction sites on a chiral 1,1'-bi-2,2'-naphthol-based fluorescent probe. It can respond specifically to D-arginine, while producing no response when in contact with all other amino acids. The probe can report arginine's concentration, and enantiomeric configuration and colorimetric studies enable its qualitative determination.

Indexed as

Analytical chemistryAnalytical chemistry applicationsChemistry

Identifiers

PMID36060051
PMCPMC9437853

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.