Evidence map›Paper›PMID 36059980›Full record

ArticleFrontiers in pharmacology2022

Activin receptor-like kinase 7 promotes apoptosis of vascular smooth muscle cells

Shengchuan Cao, Qiuhuan Yuan, Qianqian Dong, Xilong Liu, Weikang Liu, Xiaoxuan Zhai, Chuanxin Zhang, Han Liu, Mengxiong Tang, Shujian Wei and 1 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shengchuan CaoDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Qiuhuan YuanDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Qianqian DongDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Xilong LiuDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Weikang LiuDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Xiaoxuan ZhaiDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Chuanxin ZhangDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Han LiuDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Mengxiong TangDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Shujian WeiDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Yuguo ChenDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular smooth muscle cells (VSMCs) is a vital accelerator in the late phase of diabetic atherosclerosis, but the underlying mechanism remains unclear. The aim of our study was to investigate whether activin receptor-like kinase 7 (ALK7)-Smad2/3 pathway plays an important role in VSMC apoptosis of diabetic atherosclerosis. It was shown that ALK7 expression was obviously elevated in the aorta of ApoE

Indexed as

activin receptor-like kinase 7apoptosisdiabetic atherosclerosisSmad2/3vascular smooth muscle cells

Identifiers

PMID36059980
PMCPMC9428160

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.