ArticleFrontiers in medicine2022
Sarcoid-like reaction in patients with malignant tumors: Long-term clinical course and outcomes.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Delayed diagnosis of pulmonary angiosarcoma in a patient presenting with recurrent hemoptysis and widespread pulmonary nodules: a case report.Journal of medical case reports · 2026Article
- A super-elderly patient with distal biliary tract cancer and tumor-associated granuloma: a case report.Frontiers in oncology · 2026Article
- Coexisting Sarcoid Reaction and Sarcoidosis Requiring Differentiation from Pancreatic Adenocarcinoma Recurrence: A Case Report.Surgical case reports · 2026Article
- Article
- Tumor-mimicking sarcoid-like reaction with lymphoid infiltration showing intracranial extension from the left jugular foramen: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- One-year clinical follow-up of granulomatous lymphadenitis diagnosed via EBUS-TBNA in a tuberculosis-endemic region.Turkish journal of medical sciences · 2025Article
- Sarcoidosis and Cancer: The Role of the Granulomatous Reaction as a Double-Edged Sword.Journal of clinical medicine · 2024Article
- Gastrointestinal Manifestations of Sarcoidosis: A State-of-the-Art, Comprehensive Review of the Literature-Practical Clinical Insights and Many Unmet Needs on Diagnosis and Treatment.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Article
- Sarcoid-like reaction in malignant melanoma exacerbated with pembrolizumab therapy case report.Heliyon · 2024Article
- Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The development of non-caseating epithelioid cell granulomas in cancer patients who do not fulfill the systemic sarcoidosis criteria is termed sarcoid-like reaction (SLR). Little is known about this condition's natural course and impact on the prognosis of malignancy. We aimed to investigate the natural course and prognostic value of cancer-associated SLR. Methods: Clinical data were retrospectively analyzed in 32 patients with biopsy-proven cancer-associated SLR. Among patients with non-small cell lung cancer (NSCLC), SLR cases ( Results: Among the included patients, the mean age was 59.7 years, and 68.8% were female. The median follow-up period was 35.6 months [interquartile range (IQR): 14.0-61.4 months]. Of all the included malignancies ( Conclusions: During the follow-up of cancer-related SLR, we found no further evidence for systemic sarcoidosis, and most of the lesions decreased or did not change. Development of SLR was also not associated with overall survival or disease-free survival in patients with NSCLC.
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