ArticleFrontiers in medicine2022
Characterizing pharmacogenetic programs using the consolidated framework for implementation research: A structured scoping review.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Position statement from the Italian Society of Human Genetics (SIGU) on the implementation of germline pharmacogenetic testing.European journal of human genetics : EJHG · 2026Article
- Article
- Implementation of preemptive pharmacogenetic testing: progress, puzzles and priorities from an implementation science perspective.Frontiers in pharmacology · 2026Review
- Pharmacogenomics knowledge and implementation readiness among community pharmacists in Jordan: A national cross-sectional study.PloS one · 2026Article
- Preferences for implementing pharmacogenomics in pediatric primary care: a discrete choice experiment.Pediatric research · 2025Article
- Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes.Annals of human genetics · 2025Review
- Pharmacogenomics in the UK National Health Service: Progress towards implementation.British journal of clinical pharmacology · 2025Review
- Exploring the Pharmacogenetic Landscape: Identification of Clinically Relevant Genotypes by a Nation-Wide Medical Testing Laboratory in Romania.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Pre-emptive pharmacogenetic testing in the acute hospital setting: a cross-sectional study.QJM : monthly journal of the Association of Physicians · 2025Article
- Unveiling the heritability of selected unexplored pharmacogenetic markers in the Saudi population.Frontiers in pharmacology · 2025Article
- Understanding general practitioner and pharmacist preferences for pharmacogenetic testing in primary care: a discrete choice experiment.The pharmacogenomics journal · 2024Article
- Pharmacogenetics Clinical Decision Support Systems for Primary Care in England: Co-Design Study.Journal of medical Internet research · 2024Article
- Article
- An Integrated Multidisciplinary Circuit Led by Hospital and Community Pharmacists to Implement Clopidogrel Pharmacogenetics in Clinical Practice.Pharmacy (Basel, Switzerland) · 2023Article
- Cardiovascular precision medicine - A pharmacogenomic perspective.Cambridge prisms. Precision medicine · 2023Review
- The Implementation of Pharmacogenetics in the United Kingdom.Handbook of experimental pharmacology · 2023Article
- A Theory-Informed Systematic Review of Barriers and Enablers to Implementing Multi-Drug Pharmacogenomic Testing.Journal of personalized medicine · 2022Review
- Article
- Review
- Barriers and facilitators for implementing a pharmacogenetic passport: lessons learned from reusing sequencing data.PharmacogenomicsArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several healthcare organizations have developed pre-emptive pharmacogenetic testing programs, where testing is undertaken prior to the prescription of a medicine. This review characterizes the barriers and facilitators which influenced the development of these programs. A bidirectional citation searching strategy identified relevant publications before a standardized data extraction approach was applied. Publications were grouped by program and data synthesis was undertaken using the Consolidated Framework for Implementation Research (CFIR). 104 publications were identified from 40 programs and 4 multi-center initiatives. 26 (66%) of the programs were based in the United States and 95% in high-income countries. The programs were heterogeneous in their design and scale. The Characteristics of the Intervention, Inner Setting, and Process domains were referenced by 92.5, 80, and 77.5% of programs, respectively. A positive institutional culture, leadership engagement, engaging stakeholders, and the use of clinical champions were frequently described as facilitators to implementation. Clinician self-efficacy, lack of stakeholder knowledge, and the cost of the intervention were commonly cited barriers. Despite variation between the programs, there were several similarities in approach which could be categorized
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.