ArticleFrontiers in medicine2022
Role of leukocytes and systemic inflammation indexes (NLR, PLR, MLP, dNLR, NLPR, AISI, SIR-I, and SII) on admission predicts in-hospital mortality in non-elderly and elderly COVID-19 patients.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.
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Who cites it
80 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systemic inflammation index, disease severity, and mortality in patients with COVID-19: a systematic review and meta-analysis.Frontiers in immunology · 2023Pooled it
- Association between pericapsular nerve group (PENG) block and postoperative inflammatory indices and analgesic outcomes in total hip arthroplasty: a randomized controlled trial.BMC anesthesiology · 2026Trial
- The Relationship Between Severity of Apical Periodontitis and Next-Generation Systemic Inflammatory Biomarkers.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Age- and sex- related patterns in hematobiochemical and anthropometric parameters of Macaca monkeys.GeroScience · 2026Article
- The relationship between hematological indices of systemic inflammation and disease activity in patients with rheumatoid arthritis: a retrospective cross-sectional study.Clinical rheumatology · 2026Article
- Investigating Novel Inflammatory Indices and Their Links to Mortality, Cancer, and Cardiovascular Disease: A 10-Year Cohort Study.Health science reports · 2026Article
- Evaluation of Hemogram-Derived Inflammatory Markers in Healthy Cats.Veterinary sciences · 2026Article
- Assessing mortality risk in pulmonary tuberculosis and severe malnutrition: development of the IIR marker via artificial intelligence.Scientific reports · 2026Article
- The Role of the Delta Neutrophil Index, Pan-Immune Inflammation Value and Other Hematologic Inflammatory Parameters in the Preliminary Diagnosis of Tubal Ectopic Pregnancy.Immunity, inflammation and disease · 2026Article
- Preoperative Aggregate Index of Systemic Inflammation is Associated with 30-Day Postoperative Pneumonia After Minimally Invasive Esophagectomy for Esophageal Squamous Cell Carcinoma: A Retrospective Cohort Study.Infection and drug resistance · 2026Article
- What affects natural killer cell activity: a cross-sectional study.Frontiers in immunology · 2026Article
- Longitudinal trajectories of hematological indices and serum metalloproteinases-2 and 9 over 1 year after moderate and severe COVID-19.Frontiers in medicine · 2026Article
- Assessment of the aggregate index of systemic inflammation in dyslipidemia with dry eye disease: a retrospective case-control.Frontiers in ophthalmology · 2026Article
- Combined serum amyloid A and heparin-binding protein levels on admission reliably predict the severity and outcomes of COVID-19 infection in elderly patients: a retrospective study from Hangzhou, China.Annals of medicine · 2025Article
- Changes in equine complete blood count parameters and inflammatory indices with inflammation.Journal of equine veterinary science · 2025Article
- Inflammatory Indices vs. CA 125 for the Diagnosis of Early Ovarian Cancer: Evidence from a Multicenter Prospective Italian Cohort.Journal of personalized medicine · 2025Article
- Diagnostic value of full blood count derived systemic inflammatory biomarkers in malaria infection.Practical laboratory medicine · 2025Article
- The aggregate index of systemic inflammation is positively correlated with the risk of all-cause mortality in sepsis-associated acute kidney injury.Scientific reports · 2025Article
- Article
- Evaluation of Systemic Inflammation in Children with Untreated Dental Caries.Oral health & preventive dentistry · 2025Article
20 more citing papers are in PubMed but not listed here.
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6 authors.
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Abstract
Background: Systemic inflammation indices, including neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), platelet/lymphocyte ratio (PLR), derived neutrophil/lymphocyte ratio (dNLR), neutrophil/lymphocyte Methods: In a retrospective study, laboratory parameters were examined for 1,792 COVID-19 patients (elderly = 710 and non-elderly = 1,082). The ability of inflammatory markers to distinguish the severity of COVID-19 was determined by receiver operating characteristic (ROC) analysis, and survival probability was determined by the mean of Kaplan-Meier curves, with the endpoint being death. Results: In the non-survivor non-elderly and elderly patients, the parameters PLR, MLR, dNLR, NLPR, AISI, SIR-I, and SII were significantly higher than in the surviving patients. WBC count (HR = 4.668, 95% CI = 1.624 to 13.413, Conclusion: WBC count and neutrophil count in non-elderly and elderly patients, were reliable predictors of mortality.
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