Evidence map›Paper›PMID 36059578›Full record

ArticleInternational journal of women's health2022

Clinical Characteristics of Hyperandrogenism Include Hirsutism, Polycystic Ovary Syndrome, and Acne: Association with Psychiatric Disease in Women -A Nationwide Population-Based Cohort Study in Taiwan.

Tsan-Min Wang, Cheng-Hao Chou, Yi-Liang Lee, Chi-Hsiang Chung, Yao-Ching Huang, Xiao-Cheng Lai, Chien-An Sun, Chieh-Yi Kang, Gwo-Jang Wu, Wu-Chien Chien

Abstract read
In one paragraph

Article in International journal of women's health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tsan-Min WangDepartment of Medical Research, Tri-Service General Hospital, Taipei, Taiwan.
Cheng-Hao ChouDepartment of Medical Research, Tri-Service General Hospital, Taipei, Taiwan.
Yi-Liang LeeDepartment of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Chi-Hsiang ChungDepartment of Medical Research, Tri-Service General Hospital, Taipei, Taiwan.ORCID 0000-0002-4576-9900
Yao-Ching HuangDepartment of Medical Research, Tri-Service General Hospital, Taipei, Taiwan.ORCID 0000-0001-6360-3958
Xiao-Cheng LaiGraduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.ORCID 0000-0001-7867-9066
Chien-An SunDepartment of Public Health, College of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan, Republic of China.
Chieh-Yi KangChi Mei Medical Center Gynecologic Oncologist Division, Department of Obstetrics & Gynecology, Tainan City, Taiwan, Republic of China.ORCID 0000-0002-0510-8753
Gwo-Jang WuDepartment of Medical Research, Tri-Service General Hospital, Taipei, Taiwan.
Wu-Chien ChienDepartment of Medical Research, Tri-Service General Hospital, Taipei, Taiwan.ORCID 0000-0002-3286-0780

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Previous studies have shown an increased in psychiatric disorders in women with disorders associated with hyperandrogenism, but few nationwide cohorts have studied this phenomenon. Therefore, this study is aimed to examine the association between the clinical manifestations of hyperandrogenism and subsequent psychiatric disorders. Methods: Based on the National Health Insurance Research Database, 49,770 enrolled participants were matched for age and index date between January 1, 2000, and December 31, 2015. Hirsutism, polycystic ovary syndrome, and acne are characterized by hyperandrogenism. After adjusting for confounding factors, we used Cox proportional analysis to compare the risk of psychiatric disorders during the 16 years of follow-up. Results: Of all the participants, 1319 (13.25%) had psychiatric disorders in the study group, whereas only 3900(9.80%) had psychiatric disorders in the control group. After adjusting for age, and monthly income, the Cox regression analysis showed that the study patients were more likely to develop psychiatric disorders (hazard ratio [HR]: 2.004, 95% confidence interval [CI] = 1.327-2.724, P < 0.001). The results demonstrated that women aged 20-29 years had a more significant risk. Conclusion: Women with clinical characteristics of hyperandrogenism have a higher risk of developing psychiatric disorders, especially those aged 20-29 years.

Indexed as

cohort studyhyperandrogenismnational health insurance research databasepsychiatric disordersTaiwanwomen

Identifiers

PMID36059578
PMCPMC9432384

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.