Evidence map›Paper›PMID 36059381›Full record

ArticleRadiology. Cardiothoracic imaging2022

Contrast-enhanced MR Angiography without Gadolinium-based Contrast Material: Clinical Applications Using Ferumoxytol.

Mohammad H Jalili, Tiffany Yu, Cameron Hassani, Ashley E Prosper, J Paul Finn, Arash Bedayat

Abstract read
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad H Jalili *Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suite 3371, Los Angeles, CA 90095.ORCID https://orcid.org/0000-0002-3366-3869
Tiffany Yu *Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suite 3371, Los Angeles, CA 90095.ORCID 0000-0002-8722-2700
Cameron HassaniDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suite 3371, Los Angeles, CA 90095.ORCID 0000-0002-2831-5384
Ashley E ProsperDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suite 3371, Los Angeles, CA 90095.
J Paul FinnDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suite 3371, Los Angeles, CA 90095.ORCID 0000-0002-4534-7572
Arash BedayatDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suite 3371, Los Angeles, CA 90095.ORCID 0000-0001-8769-0224

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular imaging can be challenging because of the wide variability of contrast dynamics in different vascular territories and potential safety concerns in patients with renal insufficiency or allergies. Off-label diagnostic use of ferumoxytol, a superparamagnetic iron nanoparticle approved for therapy, is a promising alternative to gadolinium-based contrast agents for MR angiography (MRA). Ferumoxytol has exhibited a reassuring safety profile when used within the dose range recommended for diagnostic imaging. Because of its prolonged and stable intravascular residence, ferumoxytol can be used in its steady-state distribution for a wide variety of imaging indications, including some where conventional MRA is unreliable. In this article, authors discuss some of the major vascular applications of ferumoxytol and highlight how it may be used to provide highly diagnostic images and improve the quality, workflow, and reliability of vascular imaging.

Indexed as

CardiacMR AngiographyMRI Contrast AgentVascular

Identifiers

PMID36059381
PMCPMC9434982

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.