Evidence map›Paper›PMID 36059376›Full record

ArticleSSM - population health2022

Greenspace and mortality in the U.K. Biobank: Longitudinal cohort analysis of socio-economic, environmental, and biomarker pathways.

Shiyu Wan, David Rojas-Rueda, Jules Pretty, Charlotte Roscoe, Peter James, John S Ji

Abstract read
In one paragraph

Article in SSM - population health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Greenness and averted mortality in 390 cities in China (2000-2020).The Lancet regional health. Western Pacific · 2025
    Article
  9. Greenspaces And Cardiovascular Health.Circulation research · 2024
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shiyu WanVanke School of Public Health, Tsinghua University, Beijing, China.
David Rojas-RuedaDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.
Jules PrettySchool of Life Sciences, University of Essex, Colchester, UK.
Charlotte RoscoeChanning Division of Network Medicine, Department of Medicine, Brighamand Women's Hospital and Harvard Medical School, 401 Park Dr, 3rdFloor West, Boston, MA, 02215, USA.
Peter JamesDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, 401 Park Dr, 3rd Floor West, Boston, MA, 02215, USA.
John S JiVanke School of Public Health, Tsinghua University, Beijing, China.

Funding

Built Environment Assessment through Computer visiON (BEACON): Applying Deep Learning to Street-Level and Satellite Images to Estimate Built Environment Effects on Cardiovascular HealthR01HL150119 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JAMES, PETER · 2020 to 2024
$3.9M
Medical Research Council MC_PC_17228Medical Research Council MC_QA137853NHLBI NIH HHS R01 HL150119
6 · The paper itself

Abstract

Exposure to natural greenspace benefits health through direct and indirect pathways: increasing physical activity, improving mental health, relieving social isolation, reducing exposure to extreme temperature, noise, and air pollution. Understanding the etiologic pathway of greenspace and health is needed. Here, we used a large cohort follow-up data from the U.K. Biobank to quantify the magnitude of behavioural factors, psychological factors, biomarkers/physiological measurements, co-morbid diseases, and environmental exposure as potential mediators in the relationship between greenspace and mortality. We estimated hazard ratios (HR) with Cox proportional hazards models, and undertook exploratory mediation analyses to quantify the relative contribution of five types of mediators. Our results indicate greenspace was strongly associated with lower mortality risks [per IQR of public greenspace (HR = 0.90 (95% CI 0.86-0.84)) and domestic gardens (HR = 0.91, (95% CI 0.88-0.94))]. The protective associations were especially pronounced among those with lower individual-level socioeconomic status or living in places with area-level deprivation. Exploratory mediation analysis detected benefits in pathways through reducing air pollution, relieving social isolation and depression, increased physical activity and time spent outdoor, better lung function (FEV1/FVC), and having higher serum vitamin D levels.

Identifiers

PMID36059376
PMCPMC9429791

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.