ArticleMolecules and cells2022
Lysosome Inhibition Reduces Basal and Nutrient-Induced Fat Accumulation in
Article in Molecules and cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Article
- Supplementation with commercially available probiotic bacterial strains reduces fat accumulation inmicroPublication biology · 2026Article
- Functional Testing of Human Disease Missense Variants inKidney international reports · 2025Article
- HLH-30/TFEB mediates sexual dimorphism in immunity inAutophagy · 2025Article
- Sweet pepper extract reduces fat storage inFood science & nutrition · 2024Article
- The Role of mRNA Quality Control in the Aging ofMolecules and cells · 2023Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
A long-term energy nutritional imbalance fundamentally causes the development of obesity and associated fat accumulation. Lysosomes, as nutrient-sensing and lipophagy centers, critically control cellular lipid catabolism in response to nutrient deprivation. However, whether lysosome activity is directly involved in nutrient-induced fat accumulation remains unclear. In this study, worm fat accumulation was induced by 1 mM glucose or 0.02 mM palmitic acid supplementation. Along with the elevation of fat accumulation, lysosomal number and acidification were also increased, suggesting that lysosome activity might be correlated with nutrient-induced fat deposition in
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Registered trials
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