ArticleThoracic cancer2022
Virtual navigation bronchoscopy-guided intraoperative indocyanine green localization in simultaneous surgery for multiple pulmonary nodules.
Article in Thoracic cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 8 citations in OpenAlex.
- Clinical evaluation of the effectiveness of laser localization system in CT-guided percutaneous lung puncture positioning: a prospective randomized controlled pilot study.Quantitative imaging in medicine and surgery · 2026Article
- Article
- Feasibility and Safety of CIOS Spin for One-Stop Pulmonary Nodule Localization and Resection.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Multidisciplinary team management is associated with improved patient-centered outcomes in multiple pulmonary nodules: a prospective observational cohort study.Frontiers in oncology · 2026Article
- Precise localization techniques for small pulmonary nodules: what is next?Journal of thoracic disease · 2025Review
- Improving accuracy in percutaneous lung puncture using thoracic respiratory synchronization and laser angle guidance.Frontiers in medical technology · 2025Article
- Indocyanine green localization for preoperative CT-guided localization of multiple pulmonary nodules.Thoracic cancer · 2024Article
- Preoperative localization of pulmonary nodules by electromagnetic navigation bronchoscopy combined with methylene blue injection.Journal of thoracic disease · 2024Article
- Advances in the localization of pulmonary nodules: a comprehensive review.Journal of cardiothoracic surgery · 2024Review
- Accurate and non-invasive localization of multi-focal ground-glass opacities via electromagnetic navigation bronchoscopy assisting video-assisted thoracoscopic surgery: a single-center study.Frontiers in oncology · 2023Article
- Virtual navigation bronchoscopy-guided intraoperative indocyanine green localization in simultaneous surgery for multiple pulmonary nodules.Thoracic cancer · 2022Article
- [Highlights 57th SEPAR Congress].Open respiratory archivesReview
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7 authors at 1 institution in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAccurate localization of pulmonary nodules is the main difficulty experienced in wedge resection. Commonly used localization methods have their own advantages and disadvantages. However, clinical work has demonstrated that intraoperative indocyanine green localization under electromagnetic navigation bronchoscopy/virtual navigation bronchoscopy (VNB) is more advantageous than conventional methods for patients with multiple pulmonary nodules undergoing simultaneous surgery, especially for those undergoing bilateral lung surgery.
methodsData of patients undergoing simultaneous surgery for multiple pulmonary nodules with preoperative methylene blue localization by computed tomography (CT)-guided percutaneous lung puncture (methylene blue group) or intraoperative indocyanine green localization under VNB (virtual navigation group) were retrospectively analyzed. Patient characteristics, pulmonary nodule features, localization time, preoperative location time, location success rate, operation time, complication incidence, visceral pleural staining rate after localization, and pulmonary nodule primary resection success rate were compared between the two groups.
resultsThe methylene blue and virtual navigation groups comprised 39 and 20 patients with 119 and 67 pulmonary nodules resected, respectively. Sex, age, number of pulmonary nodules resected simultaneously, unilateral/bilateral lung surgery, pulmonary nodule size, distance between pulmonary nodules and the visceral pleura, pulmonary nodule consolidation-to-tumor ratio, location of pulmonary nodules in the pulmonary lobe, postoperative pathology, visceral pleura staining rate, primary pulmonary nodule resection success rate, and surgical duration did not differ significantly between the groups (p > 0.05). The localization time of the virtual navigation group was significantly shorter than that of the methylene blue group (p < 0.05), regardless of unilateral or bilateral multiple nodules. In the methylene blue group, 25.64% (10/39) of patients presented complications, all of which were pneumothorax, whereas no complications were found in the virtual navigation group.
conclusionsFor patients with multiple pulmonary nodules undergoing simultaneous surgery, indocyanine green injection under VNB can achieve a similar effect on pulmonary nodule localization as classical methylene blue injection under CT-guided percutaneous lung puncture, with shorter localization time and fewer complications.
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