Evidence map›Paper›PMID 36057916›Full record

ArticleInternational ophthalmology2023

Clinical features associated with the atrophy of fellow eyes in patients with unilateral type 3 macular neovascularization.

Mihyun Choi, Eun Gyu Yoon, Ki Tae Nam, Cheolmin Yun

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Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Mihyun ChoiDepartment of Ophthalmology, Korea University College of Medicine, 148 Gurodong-ro, Guro-gu, Seoul, Korea.
Eun Gyu YoonDepartment of Ophthalmology, Korea University College of Medicine, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, Seoul, Korea.
Ki Tae NamDepartment of Ophthalmology, Jeju University College of Medicine, Jeju, Korea.
Cheolmin YunDepartment of Ophthalmology, Korea University College of Medicine, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, Seoul, Korea. yuncheolmin@korea.ac.kr.ORCID http://orcid.org/0000-0002-7438-3660
Korea University · KR

Funding

Korea University K2212011
6 · The paper itself

Abstract

purposeWe sought to investigate the clinical features of eyes with unilateral type 3 macular neovascularization (MNV) according to the degenerative features of fellow eyes.

methodsWe retrospectively reviewed 55 patients with unilateral type 3 MNV and identified degenerative features including geographic atrophy (GA) in fellow eyes using multimodal imaging. Then, the clinical features of eyes with type 3 MNV at baseline and during follow-up with anti-vascular endothelial growth factor treatment and an as-needed regimen were compared according to the degenerative features of fellow eyes.

resultsEighteen patients (32.7%) had GA in fellow eyes; initial disease manifestations of type 3 MNV eyes including stage, best-corrected visual acuity, and choroidal thickness (CT) did not vary between groups (all P > 0.05). During follow-up, a rate of complete fluid resolution after three monthly loading injections was not associated with GA in fellow eyes (P = 0.703), while a lower rate of early recurrence within 3 months after loading treatment was associated with thinner CT in type 3 MNV eyes and GA over one disc area in fellow eyes (P = 0.025 and P = 0.021).

conclusionDegenerative features of fellow eyes in patients with unilateral type 3 MNV may be associated with the clinical characteristics of affected eyes.

Indexed as

Choroidal NeovascularizationGeographic AtrophyWet Macular DegenerationAngiogenesis InhibitorsAtrophyFluorescein AngiographyHumansRetrospective StudiesTomography, Optical CoherenceAngiogenesis InhibitorsAge-related macular degenerationGeographic atrophyOptical coherence tomographyRetinal pigment epithelium and outer retinal atrophyType 3 macular neovascularization

Identifiers

PMID36057916
OpenAlexW4294555443

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.