Evidence map›Paper›PMID 36057762›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2022

VanA-Enterococcus faecalis in Poland: hospital population clonal structure and vanA mobilome.

Ewa Wardal, Dorota Żabicka, Waleria Hryniewicz, Ewa Sadowy

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Deciphering vancomycin resistance inFrontiers in microbiology · 2025
    Article
  4. Article
  5. Article
  6. High prevalence and plasmidome diversity ofFrontiers in microbiology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ewa WardalDepartment of Molecular Microbiology, National Medicines Institute, Chełmska 30/34, 00-725, Warsaw, Poland.
Dorota ŻabickaDepartment of Epidemiology and Clinical Microbiology, National Medicines Institute, Chełmska 30/34, 00-725, Warsaw, Poland.
Waleria HryniewiczDepartment of Epidemiology and Clinical Microbiology, National Medicines Institute, Chełmska 30/34, 00-725, Warsaw, Poland.
Ewa SadowyDepartment of Molecular Microbiology, National Medicines Institute, Chełmska 30/34, 00-725, Warsaw, Poland. e.sadowy@nil.gov.pl.ORCID http://orcid.org/0000-0003-0284-6440
Narodowy Instytut Leków · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego SPUB MIKROBANKMinisterstwo Zdrowia (PL) Narodowy Program Ochrony Antybiotyków (NPOA)Narodowe Centrum Nauki UMO-2014/15/N/NZ7/02960
6 · The paper itself

Abstract

The aim of our study was to characterize the epidemiological situation concerning nosocomial vancomycin-resistant Enterococcus faecalis of VanA-phenotype (VREfs-VanA) in Poland by investigating their clonal relationships and the vanA-associated mobilome. One-hundred twenty-five clinical isolates of VREfs-VanA collected between 2004 and 2016 were studied by phenotypic assays, multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE), PCR detection of plasmid-specific genes, and Tn1546 structure and localization mapping. Selected isolates were subjected to PFGE-S1, Southern hybridization, genomic sequencing and conjugation experiments. The majority of isolates (97.6%) belonged to clonal complexes CC2 and CC87 of E. faecalis. All isolates were resistant to vancomycin and teicoplanin, and resistance to ciprofloxacin and aminoglycosides (high level) was very prevalent in this group. VanA phenotype was associated with 16 types of Tn1546, carrying insertion sequences IS1216, ISEfa4, IS1251 and IS1542, located on repUS1

Indexed as

Enterococcus faeciumGram-Positive Bacterial InfectionsAminoglycosidesBacterial ProteinsCarbon-Oxygen LigasesCiprofloxacinDNA Transposable ElementsEnterococcus faecalisHospitalsHumansMultilocus Sequence TypingPolandTeicoplaninVancomycinAminoglycosidesBacterial ProteinsCarbon-Oxygen LigasesCiprofloxacinDNA Transposable ElementsTeicoplaninVancomycinEnterococcus faecalisHAIPlasmidTn1546VRE

Identifiers

PMID36057762
PMCPMC9489580
OpenAlexW4294530918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.