Evidence map›Paper›PMID 36057639›Full record

ArticleNature communications2022

The genus Serratia revisited by genomics.

David J Williams, Patrick A D Grimont, Adrián Cazares, Francine Grimont, Elisabeth Ageron, Kerry A Pettigrew, Daniel Cazares, Elisabeth Njamkepo, François-Xavier Weill, Eva Heinz and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Spread of carbapenemase-producingEmerging microbes & infections · 2026
    Article
  3. A standardized workflow for typing S. marcescens outbreaks using FT-IR spectroscopy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Clinical Analysis ofPathogens (Basel, Switzerland) · 2026
    Article
  9. International journal of molecular sciences · 2026
    Review
  10. Draft genome sequence ofMicrobiology resource announcements · 2026
    Article
  11. From Environmental Organism to Nosocomial Threat:Antibiotics (Basel, Switzerland) · 2026
    Review
  12. Prevalence and activity of class II microcins inApplied and environmental microbiology · 2026
    Article
  13. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Review
  14. Draft genome sequence ofMicrobiology resource announcements · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Isolation and Genome Analysis ofMicroorganisms · 2025
    Article
  19. Article
  20. Microorganisms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

David J WilliamsDivision of Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee, UK.ORCID 0000-0003-4033-0867
Patrick A D GrimontUnité Biodiversité des Bactéries Pathogènes Emergentes, INSERM Unité 389, Institut Pasteur, Paris, France.ORCID 0000-0002-6264-136X
Adrián CazaresWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID 0000-0001-6242-4405
Francine GrimontUnité Biodiversité des Bactéries Pathogènes Emergentes, INSERM Unité 389, Institut Pasteur, Paris, France.
Elisabeth AgeronUnité Biodiversité des Bactéries Pathogènes Emergentes, INSERM Unité 389, Institut Pasteur, Paris, France.
Kerry A PettigrewSchool of Medicine, University of St Andrews, St Andrews, UK.ORCID 0000-0002-6027-0462
Daniel CazaresWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Elisabeth NjamkepoInstitut Pasteur, Université de Paris, Unité des Bactéries Pathogènes Entériques, Paris, France.
François-Xavier WeillInstitut Pasteur, Université de Paris, Unité des Bactéries Pathogènes Entériques, Paris, France.ORCID 0000-0001-9941-5799
Eva HeinzWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID 0000-0003-4413-3756
Matthew T G HoldenSchool of Medicine, University of St Andrews, St Andrews, UK.ORCID 0000-0002-4958-2166
Nicholas R ThomsonWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. nrt@sanger.ac.uk.ORCID 0000-0002-4432-8505
Sarah J CoulthurstDivision of Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee, UK. s.j.coulthurst@dundee.ac.uk.ORCID 0000-0002-0808-1875

Funding

Department of Health NIHR200639Wellcome Trust 104556Wellcome Trust 109118Wellcome Trust 206194Wellcome Trust 220321
6 · The paper itself

Abstract

The genus Serratia has been studied for over a century and includes clinically-important and diverse environmental members. Despite this, there is a paucity of genomic information across the genus and a robust whole genome-based phylogenetic framework is lacking. Here, we have assembled and analysed a representative set of 664 genomes from across the genus, including 215 historic isolates originally used in defining the genus. Phylogenomic analysis of the genus reveals a clearly-defined population structure which displays deep divisions and aligns with ecological niche, as well as striking congruence between historical biochemical phenotyping data and contemporary genomics data. We highlight the genomic, phenotypic and plasmid diversity of Serratia, and provide evidence of different patterns of gene flow across the genus. Our work provides a framework for understanding the emergence of clinical and other lineages of Serratia.

Indexed as

Genome, BacterialGenomicsPhylogenyPlasmidsSerratia

Identifiers

PMID36057639
PMCPMC9440931

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.