Evidence map›Paper›PMID 36057602›Full record

ArticleBMC urology2022

Fascial dehiscence after radical cystectomy: Is abdominal exploration mandatory?

Paz Lotan, Shayel Bercovich, Daniel Keidar, Kamil Malshy, Ziv Savin, Rennen Haramaty, Jonathan Gal, Jonathan Modai, Dan Leibovici, Roy Mano and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Paz LotanDepartment of Urology,, Rabin Medical Center, 49372, Petach Tikva, Israel. pazlotan@gmail.com.ORCID http://orcid.org/0000-0002-2951-3905
Shayel BercovichDepartment of Urology,, Rabin Medical Center, 49372, Petach Tikva, Israel.
Daniel KeidarDepartment of Urology,, Rabin Medical Center, 49372, Petach Tikva, Israel.
Kamil MalshyDepartment of Urology, Rambam Health Care Campus, Haifa, Israel.
Ziv SavinSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Rennen HaramatySackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Jonathan GalSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Jonathan ModaiSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Dan LeiboviciSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Roy ManoSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Barak RosenzweigSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Azik HoffmanDepartment of Urology, Rambam Health Care Campus, Haifa, Israel.
Miki HaiflerSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Jack BanielDepartment of Urology,, Rabin Medical Center, 49372, Petach Tikva, Israel.
Shay GolanDepartment of Urology,, Rabin Medical Center, 49372, Petach Tikva, Israel.
Tel Aviv University · ILTechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFascial dehiscence after radical cystectomy may have serious clinical implications. To optimize its management, we sought to describe accompanying intraabdominal findings of post-cystectomy dehiscence repair and determine whether a thorough intraabdominal exploration during its operation is mandatory.

methodsWe retrospectively reviewed a multi-institutional cohort of patients who underwent open radical cystectomy between 2005 and 2020. Patients who underwent exploratory surgery due to fascial dehiscence within 30 days post-cystectomy were included in the analysis. Data collected included demographic characteristics, the clinical presentation of dehiscence, associated laboratory findings, imaging results, surgical parameters, operative findings, and clinical implications. Potential predictors of accompanying intraabdominal complications were investigated.

resultsOf 1301 consecutive patients that underwent cystectomy, 27 (2%) had dehiscence repair during a median of 7 days post-surgery. Seven patients (26%) had accompanying intraabdominal pathologies, including urine leaks, a fecal leak, and an internal hernia in 5 (19%), 1 (4%), and 1 (4%) patients, respectively. Accompanying intraabdominal findings were associated with longer hospital stay [20 (IQR 17, 23) vs. 41 (IQR 29, 47) days, P = 0.03] and later dehiscence identification (postoperative day 7 [IQR 5, 9] vs. 10 [IQR 6, 15], P = 0.03). However, the rate of post-exploration complications was similar in both groups. A history of ischemic heart disease was the only predictor for accompanying intraabdominal pathologies (67% vs. 24%; P = 0.02).

conclusionsA substantial proportion of patients undergoing post-cystectomy fascial dehiscence repair may have unrecognized accompanying surgical complications without prior clinical suspicion. While cardiovascular disease is a risk factor for accompanying findings, meticulous abdominal inspection is imperative in all patients during dehiscence repair. Identification and repair during the surgical intervention may prevent further adverse, possibly life-threatening consequences with minimal risk for iatrogenic injury.

Indexed as

CystectomyUrinary Bladder NeoplasmsHumansLength of StayPostoperative ComplicationsRetrospective StudiesUrinary BladderBladder cancerCystectomyDehiscenceFasciaLaparotomySurgery

Identifiers

PMID36057602
PMCPMC9441031
OpenAlexW4294495348

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.