Evidence map›Paper›PMID 36057594›Full record

Observational studyBMC musculoskeletal disorders2022

Sagittal alignment of the cervical spine: radiographic analysis of 111 asymptomatic adolescents, a retrospective observational study.

Yanjie Zhu, Xinkun Zhang, Yunshan Fan, Zhi Zhou, Guangfei Gu, Chuanfeng Wang, Chaobo Feng, Jia Chen, Shisheng He, Haijian Ni

Abstract readObservational Study
In one paragraph

Observational study in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Association between the anterior tilt slope and spinal sagittal parameters in asymptomatic adults from Southern China.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  4. Sagittal cervical and spinopelvic alignment in non-deformed adults: the role of T1 slope and C2-C7 Cobb angle.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  10. The standard posture is a myth: a scoping review.Journal of rehabilitation medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanjie ZhuOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Xinkun ZhangOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yunshan FanOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zhi ZhouOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Guangfei GuOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Chuanfeng WangOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Chaobo FengOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Jia ChenOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Shisheng HeOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China. hss7418@tongji.edu.cn.
Haijian NiOrthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China. nihaijianch@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the cervical spine morphology and explore its relationship to global sagittal alignment parameters in the asymptomatic adolescent population. 

methodsA total of 111 adolescent subjects were included. Sagittal alignment parameters, including C7 Slope, C2-C7 Cobb, C2-7 plumb line (PL), C2-S1 Sagittal Vertical Axis (SVA), C7-S1 SVA, T5-12 Cobb, T10-L2 Cobb, L1-S1 Cobb, pelvic incidence (PI), pelvic tilt (PT) and sacral slope (SS), were obtained from lateral radiographs. 

resultsForty-four males and sixty-seven females with a mean age of 16.12 ± 2.40 years were included in this study. The mean values of C7 Slope, C2-7 Cobb and C2-7PL were 20.45 ± 8.88°, -7.72 ± 12.10°, and 13.53 ± 11.63 mm, respectively. C2-7 Cobb, C7 Slope showed significant differences between the male and female groups. Correlation analysis showed that C7 slope was significantly correlated with C2-7 Cobb (r = -0.544, P < 0.001), C2-S1 SVA (r = 0.335, P < 0.001), and C7-S1 SVA (r = 0.310, P = 0.001), but not lumbosacral parameters(L5-S1 Cobb, PI, PT, SS). Using a modified method of Toyama to describe the cervical spine morphology, there were 37 cases (33.3%) in the Lordotic group, and C7 slope, C2-7 Cobb and C2-7PL showed significant differences between groups. According to C2-C7 Cobb, there were 80 Lordotic cases (72.1%). C7 slope and C2-7PL were significantly different between the two groups.

conclusionThe cervical spine morphology of asymptomatic adolescents varies widely, from lordotic to kyphotic. Combining different classification methods provides a better understanding of the morphology of the cervical spine. C7 slope is an important predictor of global sagittal balance and C2-7PL is a key parameter for restoring cervical lordosis, which should be considered pre-operatively and for conservative treatment. Cervical regional sagittal alignment parameters are not correlated with lumbosacral parameters, and C2-7 Cobb, C7 Slope showed significant differences between males and females.

Indexed as

KyphosisLordosisAdolescentCervical VertebraeFemaleHumansLumbar VertebraeMaleRetrospective StudiesSacrumAsymptomatic adolescentC2-7 CobbC2-7 plumb lineC7 SlopeCervical morphologySagittal alignment parameter

Identifiers

PMID36057594
PMCPMC9440571

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.