ArticleBMC neurology2022
Risk factors for early neurological deterioration in acute isolated pontine infarction without any causative artery stenosis.
Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Triglyceride Glucose Index and Stress Hyperglycemia are Important Factors for Predicting Early Neurological Deterioration in Isolated Acute Pontine Infarction.Brain and behavior · 2025Article
- Intravenous thrombolysis prevents neurological deterioration in patients with acute pontine infarction.Frontiers in neurology · 2025Article
- Predictive Factors of Early Neurologic Deterioration in Isolated Pontine Infarction.Annals of Indian Academy of Neurology · 2025Article
- Interpretable machine learning for predicting early neurological deterioration in symptomatic intracranial atherosclerotic stenosis.Frontiers in neurology · 2025Article
- MRI-based clinical-radiomics nomogram to predict early neurological deterioration in isolated acute pontine infarction: a two-center study in Northeast China.BMC neurology · 2024Article
- Association Between the Atherogenic Index of Plasma and 90-Day Clinical Prognosis in Patients with Acute Pontine Infarction: A Single Center Study.International journal of general medicine · 2024Article
- Morphological predictors of neurological deterioration in patients with acute isolated pontine infarct.Acta neurologica Belgica · 2023Article
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Authors and funding
8 authors at 3 institutions in 1 country.
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Abstract
backgroundThis study aimed to investigate the risk predictors for early neurological deterioration (END) in isolated acute pontine infarction without any causative artery stenosis.
methodsIn this retrospective study, patients with isolated acute pontine infarction within 72 h of symptom onset were enrolled between October 2017 and December 2021. END was defined as an increase in the National Institutes of Health Stroke Scale (NIHSS) score ≥ 2 points within the first week postadmission. Patients were divided into the END and the non-END groups. Multiple logistic regression analysis was used to evaluate independent predictors of END in patients with isolated acute pontine infarction.
resultsA total of 153 patients were included in the final study (62 females; mean age, 67.27 ± 11.35 years), of whom 28.7% (47 of 153) experienced END. Multiple logistic regression analyses showed that infarct volume (adjusted odds ratio [aOR], 1.003; 95% CI, 1.001-1.005; P = 0.002) and basilar artery branch disease (aOR, 3.388; 95% CI, 1.102-10.417; P = 0.033) were associated with END. The combined ROC analysis of the infarct volume and basilar artery branch disease for predicting END showed that the sensitivity and specificity were 80.9% and 72.6%, respectively.
conclusionBasilar artery branch disease and infarct volume were associated with END in acute isolated pontine infarction and may be useful prognostic factors for neurological progression.
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