ArticleJournal of affective disorders2022
Delayed circadian rhythms and insomnia symptoms in obsessive-compulsive disorder.
Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- A Systematic Review of Ecological Momentary Assessment for Obsessive-Compulsive Disorder.Journal of clinical psychology · 2026Pooled it
- A Systematic Review on Insomnia and Circadian Rhythms Desynchronization in Obsessive-Compulsive Disorder: From Childhood to Adulthood.Journal of sleep research · 2026Pooled it
- Impact of sleep disruption on BDD symptoms and treatment response.Journal of affective disorders · 2024Trial
- Article
- Different Protocols of Circadian Rhythm Disruptions Differentially Affect Locomotor Activity, and Anxiety- and Compulsive-Like Behaviors in Male vs. Female Wistar Rats along with the Significant Involvement of GSK-3β in Females.Molecular neurobiology · 2025Article
- The rollercoaster of obsessive-compulsive disorder: How chronotype and time of day affect behavioral inhibition in adults with OCD.Journal of mood and anxiety disorders · 2025Article
- Insomnia as a predictor of treatment outcomes in adolescents receiving concentrated exposure treatment for OCD.BMC psychiatry · 2024Article
- Disruption of neural periodicity predicts clinical response after deep brain stimulation for obsessive-compulsive disorder.Nature medicine · 2024Article
- BNST GABAergic neurons modulate wakefulness over sleep and anesthesia.Communications biology · 2024Article
- Level 2 Polysomnography for the Diagnosis of Sleep Disorders: A Health Technology Assessment.Ontario health technology assessment series · 2024Article
- Lessons learned from a multimodal sensor-based eHealth approach for treating pediatric obsessive-compulsive disorder.Frontiers in digital health · 2024Article
- Wearable and Mobile Technologies for the Evaluation and Treatment of Obsessive-Compulsive Disorder: Scoping Review.JMIR mental health · 2023Article
- Sleep disorders related to index and comorbid mental disorders and psychotropic drugs.Annals of general psychiatry · 2023Article
- Case report: Diagnosis and intervention of a non-24-h sleep-wake disorder in a sighted child with a psychiatric disorder.Frontiers in psychiatry · 2023Article
- Obsessive-compulsive symptoms and dissociative experiences: Suggested underlying mechanisms and implications for science and practice.Frontiers in psychology · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAccumulating evidence implicates sleep and circadian rhythm disturbance in obsessive-compulsive disorder (OCD). However, a multimethod characterization of sleep and circadian rhythms in OCD, their association with symptom severity, and the functional relationship between these variables is lacking.
methodsThe present study measured multiple indicators of sleep and circadian rhythms in a sample of adults with OCD, adults without OCD, and healthy controls (n = 74). Participants completed measures of morningness-eveningness, delayed sleep-wake phase disorder (DSWPD), insomnia symptoms, and OCD symptoms, as well as one week of sleep monitoring via a sleep diary and actigraphy.
resultsDelayed circadian rhythms (higher eveningness, later mid-sleep timing, and higher rates of DSWPD) and higher insomnia symptoms were observed in those with OCD compared to healthy controls, as well as associations between delayed circadian rhythms and insomnia symptoms and OCD symptom severity across the full sample. Further, insomnia symptoms mediated the relationship between delayed circadian rhythms and OCD symptoms. In contrast, there were no links between total sleep time or sleep quality and OCD. LIMITATIONS: Data collection during COVID-19 pandemic, correlational data, no physiological measure of circadian rhythms.
conclusionsThese findings highlight a robust association between delayed circadian rhythms and OCD and suggest insomnia symptoms may be one mechanism in this relationship. Sleep and circadian rhythm disturbance may be novel targets for OCD treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.