Evidence map›Paper›PMID 36057007›Full record

ReviewInternational ophthalmology2023

The 100 most cited papers on amblyopia: a bibliographic perspective.

Gilad Allon, Elad Moisseiev, Sara Dichter, Tamara Wygnanski-Jaffe, Eedy Mezer

Abstract readReview
PubMed Publisher
In one paragraph

Review in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Multi-Feature Mapping of Distortions in Amblyopia With Localized Sampling.Investigative ophthalmology & visual science · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gilad AllonRetina Service, Moorfields Eye Hospital, London, UK. drgiladallon@gmail.com.
Elad MoisseievDepartment of Ophthalmology, Meir Medical Center, Kfar Saba, Israel.
Sara DichterBruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.
Tamara Wygnanski-JaffeSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Eedy MezerBruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyze the top 100 most cited papers related to amblyopia.

methodsA bibliographic search in the Institute for Scientific Information Web of Knowledge across 55 years was performed.

resultsEighty-nine of the 100 papers were published in first-quartile journals. Half (50) of the senior authors were from the USA. Most papers dealt with clinical science (72) and included original research (84). Forty-two of the articles related to all three types of amblyopia (refractive, strabismic and deprivation). Thirty-four related to both strabismic and refractive amblyopia. Around two-thirds of the papers dealt with treatment (34) and pathophysiology (30). Almost a quarter (23%) of the papers were multicenter studies. Nearly half (48) of the papers were published between 2000 and 2010. The Pediatric Eye Disease Investigator Group (PEDIG) published the highest number of studies (11), which dealt more with treatment (p = 0.01) and had higher average number of citations per years (p = 0.05). A larger number of articles on the treatment of amblyopia are newer (p = 0.01). There was no correlation between the time of their publication and the number of citations (p = 0.68, r = 0.042).

conclusionsHalf of the papers were published between 2000 and 2010 and were spearheaded by PEDIG. Most papers dealt with treatment and pathophysiology. This study provides an important historical perspective, emphasizing the need for additional research to better understand this preventable and curable childhood vision impairment.

Indexed as

AmblyopiaChildHumansRefraction, OcularVision TestsAmblyopiaBibliographyCitationsDevelopment of vision

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.