Evidence map›Paper›PMID 36056555›Full record

ArticleBiophysical journal2022

Calcium-induced environmental adaptability of the blood protein vitronectin.

Ye Tian, Kyungsoo Shin, Alexander E Aleshin, Wonpil Im, Francesca M Marassi

Open access · greenAbstract read
In one paragraph

Article in Biophysical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ye TianSanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Kyungsoo ShinSanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Alexander E AleshinSanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Wonpil ImDepartments of Biological Sciences, Chemistry, and Bioengineering, Lehigh University, Bethlehem, Pennsylvania.
Francesca M MarassiSanford Burnham Prebys Medical Discovery Institute, La Jolla, California. Electronic address: fmarassi@sbp.edu.
Sanford Burnham Prebys Medical Discovery Institute · USLehigh University · US

Funding

Tumor Microenvironment and Cancer ImmunologyP30CA030199 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI ELENA B PASQUALE · 1985 to 2026
$107.2M
Membrane Protein Effectors of Pathogen Interactions With HostR35GM118186 · NIGMS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Francesca M Marassi · 2016 to 2026
$8.5M
NCI NIH HHS P30 CA030199NIGMS NIH HHS R35 GM118186
6 · The paper itself

Abstract

The adaptability of proteins to their work environments is fundamental for cellular life. Here, we describe how the hemopexin-like domain of the multifunctional blood glycoprotein vitronectin binds Ca

Indexed as

CalciumVitronectinBinding SitesCrystallography, X-RayHemopexinProtein BindingProtein ConformationCalciumHemopexinVitronectin

Identifiers

PMID36056555
PMCPMC9674982
OpenAlexW4294190640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.