Evidence map›Paper›PMID 36056457›Full record

ArticleGlobal change biology2022

Climate drives the spatiotemporal dynamics of scrub typhus in China.

Fangyu Ding, Qian Wang, Mengmeng Hao, Richard James Maude, Nicholas Philip John Day, Shengjie Lai, Shuai Chen, Liqun Fang, Tian Ma, Canjun Zheng and 1 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Global change biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07124949 (Chinese Migrant Population Health Cohort), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07124949 recruitingnot on this mapstarted 2025, after this paper: background citation

Chinese Migrant Population Health Cohort

TypeobservationalSponsorJinwei TianRan2025 to 2030Enrolled26,000ConditionsCardiovascular Diseases, Metabolic Disorders, Ageing and Geriatric Health, Climate AdaptationArmsNo intervention
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Global and regional seroprevalence, incidence, mortality of, and risk factors for scrub typhus: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024
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  17. Predicting the potential distribution areas ofFrontiers in public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Fangyu DingInstitute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0003-1821-531X
Qian WangNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.ORCID 0000-0002-7102-4232
Mengmeng HaoInstitute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0003-4025-3291
Richard James MaudeNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.ORCID 0000-0002-5355-0562
Nicholas Philip John DayNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.ORCID 0000-0003-2309-1171
Shengjie LaiWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, UK.ORCID 0000-0001-9781-8148
Shuai ChenInstitute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0003-3623-1532
Liqun FangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.ORCID 0000-0002-4981-1483
Tian MaInstitute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0001-9980-3329
Canjun ZhengChinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0001-6822-8755
Dong JiangInstitute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0002-4154-5969
Chinese Academy of Sciences · CNMahidol University · THChinese Center For Disease Control and Prevention · CNHarvard University · USInstitute of Microbiology · CNUniversity of Southampton · GB

Funding

Wellcome Trust 220211
6 · The paper itself

Abstract

Scrub typhus is a climate-sensitive and life-threatening vector-borne disease that poses a growing public health threat. Although the climate-epidemic associations of many vector-borne diseases have been studied for decades, the impacts of climate on scrub typhus remain poorly understood, especially in the context of global warming. Here we incorporate Chinese national surveillance data on scrub typhus from 2010 to 2019 into a climate-driven generalized additive mixed model to explain the spatiotemporal dynamics of this disease and predict how it may be affected by climate change under various representative concentration pathways (RCPs) for three future time periods (the 2030s, 2050s, and 2080s). Our results demonstrate that temperature, precipitation, and relative humidity play key roles in driving the seasonal epidemic of scrub typhus in mainland China with a 2-month lag. Our findings show that the change of projected spatiotemporal dynamics of scrub typhus will be heterogeneous and will depend on specific combinations of regional climate conditions in future climate scenarios. Our results contribute to a better understanding of spatiotemporal dynamics of scrub typhus, which can help public health authorities refine their prevention and control measures to reduce the risks resulting from climate change.

Indexed as

Scrub TyphusChinaClimate ChangeGlobal WarmingHumansTemperatureclimate changeimpactspublic healthscrub typhusspatiotemporal dynamicvector-borne disease

Identifiers

PMID36056457
PMCPMC9825873
OpenAlexW4294415255

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.