Evidence map›Paper›PMID 36056218›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2023

Bailout left atrial appendage occluder for pulmonary vein isolation and electrical cardioversion in patients with atrial fibrillation and left atrial appendage thrombus: a pilot study.

Chin-Feng Tsai, Pang-Shuo Huang, Fu-Chun Chiu, Jien-Jiun Chen, Sheng-Nan Chang, Jung-Cheng Hsu, Su-Kiat Chua, Hsiao-Liang Cheng, Yi-Chih Wang, Juey-Jen Hwang and 1 more

Abstract read
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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Chin-Feng TsaiSchool of Medicine, Chung Shan Medical University, Taichung City, 401, Taiwan.
Pang-Shuo HuangDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Dou-Liu City, 640, Taiwan.
Fu-Chun ChiuDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Dou-Liu City, 640, Taiwan.
Jien-Jiun ChenDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Dou-Liu City, 640, Taiwan.
Sheng-Nan ChangDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Dou-Liu City, 640, Taiwan.
Jung-Cheng HsuDivision of Cardiology, Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, 220, Taiwan.
Su-Kiat ChuaDivision of Cardiology, Department of Internal Medicine, Shin-Kong Memorial Wu Ho-Su Hospital, Taipei City, 111, Taiwan.
Hsiao-Liang ChengDepartment of Anesthesia, National Taiwan University Hospital, Taipei City, 100, Taiwan.
Yi-Chih WangCardiovascular Center, National Taiwan University Hospital, Taipei City, 100, Taiwan.
Juey-Jen HwangDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Dou-Liu City, 640, Taiwan.
Chia-Ti TsaiCardiovascular Center, National Taiwan University Hospital, Taipei City, 100, Taiwan. cttsai1999@gmail.com.ORCID http://orcid.org/0000-0002-4853-8665
National Taiwan University Hospital · TWChung Shan Medical University Hospital · TWFar Eastern Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardioversion and catheter-based circumferential pulmonary vein isolation (CPVI) are established rhythm control treatment strategies for patients with atrial fibrillation (AF). However, these treatments are contraindicated for AF patients with a left atrial appendage (LAA) thrombus.

methodsWe conducted the first-in-man case series study to evaluate the feasibility and safety of performing cardioversion or CPVI in AF patients with LAA thrombus immediately after implantation of LAA Occluder (LAAO) in a combined procedure. In our multi-center LAAO registry of 310 patients, 27 symptomatic and drug-refractory AF patients underwent a combined procedure of LAAO and CPVI, among whom 10 (mean age 68 ± 16 years, 6 men) having anticoagulant-resistant LAA thrombus received a bailout procedure of LAAO implantation first then CPVI, and the other 17 patients without LAA thrombus received CPVI first then LAAO for comparison.

resultsThe mean CHA

conclusionWe demonstrated that cardioversion or CPVI is doable in symptomatic AF patients with LAA thrombus if LAA was occluded ahead as a bailout procedure.

Indexed as

Atrial AppendageAtrial FibrillationHeart DiseasesPulmonary VeinsThrombosisAgedAged, 80 and overElectric CountershockHumansMaleMiddle AgedPilot ProjectsTreatment OutcomeCircumferential pulmonary vein isolationElectrical cardioversionLeft atrial appendage occluderLeft atrial appendage thrombus

Identifiers

PMID36056218
OpenAlexW4294311473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.