Evidence map›Paper›PMID 36055957›Full record

ReviewEuropean urology focus2022

Moving Prostate Cancer Polygenic Risk Scores from Research Towards Clinical Practice.

James T Kearns, Brian T Helfand, Jianfeng Xu

Abstract readReview
PubMed Publisher
In one paragraph

Review in European urology focus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

James T KearnsLevine Cancer Institute, Charlotte, NC, USA. Electronic address: james.kearns@atriumhealth.org.
Brian T HelfandDepartment of Surgery, NorthShore University HealthSystem, Evanston, IL, USA; Program for Personalized Cancer Care, NorthShore University HealthSystem, Evanston, IL, USA.
Jianfeng XuDepartment of Surgery, NorthShore University HealthSystem, Evanston, IL, USA; Program for Personalized Cancer Care, NorthShore University HealthSystem, Evanston, IL, USA.
NorthShore University HealthSystem · USLevine Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in our understanding of genetic factors that contribute to prostate cancer (PCa) susceptibility have the potential to improve disease screening, diagnosis, and treatment. Genetic risk scores in particular can more accurately inform patients of their risk of being diagnosed with PCa, which may help in decisions on whether to undergo prostate-specific antigen screening or prostate biopsy. Genetic information may also be useful in helping patients understand the etiology of their PCa and whether their family members should undergo more intensive screening. PATIENT SUMMARY: This mini review discusses recent advances in our understanding of how genetic factors influence a man's risk of developing prostate cancer. This information has the potential to improve screening, diagnosis, and patient counseling following a diagnosis of prostate cancer.

Indexed as

Prostate-Specific AntigenProstatic NeoplasmsHumansMaleProstateRisk AssessmentRisk FactorsProstate-Specific Antigen

Identifiers

PMID36055957
OpenAlexW4293739352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.