Evidence map›Paper›PMID 36055471›Full record

ArticleVirus research2022

Genomic and epidemiologic surveillance of SARS-CoV-2 in Southern Brazil and identification of a new Omicron-L452R sublineage.

Mariana Soares da Silva, Juliana Schons Gularte, Micheli Filippi, Meriane Demoliner, Viviane Girardi, Ana Cristina Sbaraini Mosena, Vyctoria Malayhka de Abreu Góes Pereira, Alana Witt Hansen, Matheus Nunes Weber, Paula Rodrigues de Almeida and 7 more

Abstract read
In one paragraph

Article in Virus research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. SARS-CoV-2 sublineages recovered from southern Brazilian cases during Omicron wave in 2023, early introduction of JN.1.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Mariana Soares da SilvaUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil. Electronic address: marisoares.vet@gmail.com.
Juliana Schons GularteUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Micheli FilippiUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Meriane DemolinerUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Viviane GirardiUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Ana Cristina Sbaraini MosenaUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Vyctoria Malayhka de Abreu Góes PereiraUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Alana Witt HansenUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Matheus Nunes WeberUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Paula Rodrigues de AlmeidaUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Juliane Deise FleckUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.
Andrea Gurgel Batista Leite Dal BóServiço de Controle de Infecção Hospitalar do Virvi Ramos, Caxias do Sul, RS, Brazil; IMMUNESHARE - MCTI Trial, Brazil; Programa de Pós-Graduação em Saúde Coletiva, Universidade do Vale dos Sinos (UNISINOS), São Leopoldo, RS, Brazil.
Marcus Herbert JonesIMMUNESHARE - MCTI Trial, Brazil; Pesquisador do Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.
Frederico FriedrichIMMUNESHARE - MCTI Trial, Brazil; Programa de Pós-Graduação em Medicina Pediátrica e Saúde da Criança, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil; Pesquisador do Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.
Luiz Amorim FilhoIMMUNESHARE - MCTI Trial, Brazil; Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti (HEMORIO), Rio de Janeiro, RJ, Brazil.
Fábio KlamtIMMUNESHARE - MCTI Trial, Brazil; Laboratório de Bioquímica Celular, Departamento de Bioquímica, ICBS/UFRGS, Porto Alegre, RS, Brazil.
Fernando Rosado SpilkiUniversidade Feevale, Laboratório de Microbiologia Molecular, Rodovia ERS-239, N° 2755, Prédio Vermelho, Piso 1, sala 103, Vila Nova, Novo Hamburgo, RS CEP 93525-075, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, SARS-CoV-2 Omicron variant (B.1.1.529) was first identified in Botswana in November 2021. In a short period of time, this highly mutated variant replaced the previous dominant Delta variant, causing an exponential increase in the number of COVID-19 cases, resulting in a new wave of pandemic. This current research article aims to analyze and summarize information about the genetic characteristics, amino acid mutations and epidemiological data providing scientific findings to enrich the SARS-CoV-2 knowledge. More importantly, we describe here, for the first time, the identification of a new Omicron variant of concern: Omicron-L452R in Brazil.

Indexed as

COVID-19SARS-CoV-2Amino AcidsBrazilEpidemiological MonitoringGenomicsHumansAmino AcidsMutational scanningSARS-CoV-2S:L452RVOC

Identifiers

PMID36055471
PMCPMC9425700

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.