Evidence map›Paper›PMID 36054141›Full record

ArticlePloS one2022

Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia.

Wei-Tse Chiu, Yi-Hsuan Lu, Yin-Ting Chen, Yin Ling Tan, Yi-Chieh Lin, Yu-Lien Chen, Hung-Chieh Chou, Chien-Yi Chen, Ting-An Yen, Po-Nien Tsao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Wei-Tse ChiuDepartment of Pediatrics, National Taiwan University Hospital, Yun-Lin Branch, Yun-Lin, Taiwan.ORCID 0000-0003-1733-3867
Yi-Hsuan LuDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei, Taiwan.
Yin-Ting ChenDivision of Neonatology, Department of Pediatrics, Children Hospital, China Medical University, Taichung, Taiwan.
Yin Ling TanDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei, Taiwan.ORCID 0000-0003-1671-6145
Yi-Chieh LinDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei, Taiwan.ORCID 0000-0002-9633-9273
Yu-Lien ChenDepartment of Nursery, National Taiwan University Hospital, Taipei, Taiwan.
Hung-Chieh ChouDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei, Taiwan.
Chien-Yi ChenDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei, Taiwan.
Ting-An YenDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei, Taiwan.
Po-Nien TsaoDepartment of Pediatrics, National Taiwan University Children Hospital, Taipei, Taiwan.ORCID 0000-0002-6114-1769
National Taiwan University Hospital · TWChina Medical University · TWFu Jen Catholic University · TWMinistry of Health and Welfare · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn very low birth weight (VLBW) infants, hypothermia immediately following birth is common even in countries rich in medical resources. The purpose of this study is to design a standard prevention bundle that decreases the rate of hypothermia among infants after birth and to investigate efficacy of the bundle and short-term outcomes for VLBW infants.

methodsThis quality improvement project was conducted from February 2017 to July 2018 on all VLBW preterm infants admitted at a single referral level III neonatal intensive care unit. The infants were classified into the pre-intervention (February to September 2017) and post-intervention (October 2017 to July 2018) groups according to the time periods when they were recruited. During the pre-intervention period, we analyzed the primary causes of hypothermia, developed solutions corresponding to each cause, integrated all solutions into a prevention bundle, and applied the bundle during the post-intervention period. Afterwards, the incidence of neonatal hypothermia and short-term outcomes, such as intraventricular hemorrhage (IVH), acidosis, and shock requiring inotropic agents, in each group were compared.

resultsA total of 95 VLBW infants were enrolled in the study, including 37 pre-intervention, and 58 post-intervention cases. The incidence of hypothermia in preterm infants decreased significantly upon the implementation of our prevention bundle, both in the delivery room (from 45.9% to 8.6%) and on admission (59.5% to 15.5%). In addition, the short-term outcomes of VLBW infants improved significantly, especially with the decreased incidence of IVH (from 21.6% to 5.2%, P = 0.015).

conclusionsOur standardized prevention bundle for preventing hypothermia in VLBW infants is effective and decreased the IVH rate in VLBW infants. We strongly believe that this prevention bundle is a simple, low-cost, replicable, and effective tool that hospitals can adopt to improve VLBW infant outcomes.

Indexed as

HypothermiaInfant, Premature, DiseasesCerebral HemorrhageHumansInfantInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightIntensive Care Units, Neonatal

Identifiers

PMID36054141
PMCPMC9439247
OpenAlexW4294316976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.