Evidence map›Paper›PMID 36053935›Full record

ArticleAnnals of clinical and translational neurology2022

Postvaccinal GABA-B receptor antibody encephalitis after ChAdOx1 nCoV-19 vaccination.

Seon-Jae Ahn, Soon-Tae Lee, Kon Chu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Annals of clinical and translational neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Seon-Jae AhnDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.ORCID 0000-0003-0520-7812
Soon-Tae LeeDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.ORCID 0000-0003-4767-7564
Kon ChuDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.ORCID 0000-0001-5863-0302
Seoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several cases of autoimmune encephalitis have been reported after ChAdOx1 nCoV-19 (AZD1222) vaccination. We encountered a male patient who presented with generalized tonic-clonic seizures, cognitive decline, and gait disturbance that occurred suddenly after the second dose of the ChAdOx1 nCoV-19 vaccine. Clinical presentation and magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) test results were compatible with limbic encephalitis. Synaptic autoantibody tests confirmed serum and CSF GABA B receptor antibodies were present. The patient was treated with immunotherapy with intravenous immunoglobulin and rituximab. This GABA-B receptor antibody encephalitis case occurred presumably due to transient autoantibody production following vaccine administration.

Indexed as

COVID-19EncephalitisChAdOx1 nCoV-19Encephalomyelitis, Acute DisseminatedHumansImmunoglobulins, IntravenousMaleReceptors, GABA-BRituximabVaccinationChAdOx1 nCoV-19Immunoglobulins, IntravenousReceptors, GABA-BRituximab

Identifiers

PMID36053935
PMCPMC9537891
OpenAlexW4294295638

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.