Evidence map›Paper›PMID 36053881›Full record

ArticleCytometry. Part A : the journal of the International Society for Analytical Cytology2023

OMIP-085: Cattle B-cell phenotyping by an 8-color panel.

Eduard O Roos, Marie Bonnet-Di Placido, William N Mwangi, Katy Moffat, Lindsay M Fry, Ryan Waters, John A Hammond

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. OMIP-085: Cattle B-cell phenotyping by an 8-color panel.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eduard O RoosThe Pirbright Institute, Surrey, UK.ORCID 0000-0002-3679-4995
Marie Bonnet-Di PlacidoThe Pirbright Institute, Surrey, UK.ORCID 0000-0002-8299-5595
William N MwangiThe Pirbright Institute, Surrey, UK.ORCID 0000-0003-0310-4385
Katy MoffatThe Pirbright Institute, Surrey, UK.ORCID 0000-0003-0120-7196
Lindsay M FryAnimal Disease Research Unit, Agricultural Research Service, US Department of Agriculture, Pullman, Washington, USA.ORCID 0000-0003-0938-9254
Ryan WatersThe Pirbright Institute, Surrey, UK.ORCID 0000-0002-4174-1150
John A HammondThe Pirbright Institute, Surrey, UK.ORCID 0000-0002-2213-3248

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00007038Biotechnology and Biological Sciences Research Council BBS/E/I/00007039
6 · The paper itself

Abstract

This 8-color panel has been optimized to distinguish between functionally distinct subsets of cattle B cells in both fresh and cryopreserved peripheral blood mononuclear cells (PBMCs). Existing characterized antibodies against cell surface molecules (immunoglobulin light chain (S-Ig[L]), CD20, CD21, CD40, CD71, and CD138) enabled the discrimination of 24 unique populations within the B-cell population. This allows the identification of five putative functionally distinct B-cell subsets critical to infection and vaccination responses: (1) naïve B cells (B

Indexed as

B-Lymphocytes, RegulatoryAnimalsCattleCD40 AntigensFlow CytometryCD40 Antigensantibody secreting cellsB cellsB-cell subsetscattleflow cytometrymemory B cellsnaïve B cellsregulatory B cells

Identifiers

PMID36053881
PMCPMC10087846

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.