Evidence map›Paper›PMID 36053577›Full record

ArticleBMJ paediatrics open2022

Acute pancreatitis in children - morbidity and outcomes at 1 year.

A Bhanot, A A Majbar, Toby Candler, L P Hunt, E Cusick, Paul R V Johnson, Julian Ph Shield

Open access · diamondAbstract read
In one paragraph

Article in BMJ paediatrics open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Pancreatic involvement inMolecular genetics and metabolism reports · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

A BhanotFaculty of Health Sciences, University of Bristol, Bristol, UK.
A A MajbarDepartment of Paediatrics, Sabratha Teaching Hospital, Sabratha, Libya.
Toby CandlerPaediatric Diabetes and Endocrinology, University Hospitals Bristol NHS Foundation Trust, Bristol, UK toby.candler@gmail.com.ORCID 0000-0002-4587-8744
L P HuntNIHR Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, UK.
E CusickPaediatric Surgery, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Paul R V JohnsonNuffield Department of Surgery, University of Oxford, OXFORD, UK.
Julian Ph ShieldPaediatric Diabetes and Endocrinology, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.ORCID 0000-0003-2601-7575
Diabetes Australia · AUUniversity of Bristol · GBNuffield Orthopaedic Centre · GBUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity of Abuja Teaching Hospital · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo establish short-term and medium-term complications 1-year postdiagnosis, of acute pancreatitis (AP) in children aged 0-14 years.

designOne-year follow-up of a prospective monthly surveillance of new cases of AP in children under 15 years through the British Paediatric Surveillance Unit (BPSU) from April 2013 to April 2014.

settingA monthly surveillance of >3700 consultant paediatricians and paediatric surgeons in the UK and Ireland using the BPSU. PATIENTS: Children aged 0-14 years with a new diagnosis of AP.

main outcome measuresThe outcomes following AP, including the incidence of complications and comorbidity at diagnosis and at 1 year.

resultsOf the 94 new confirmed cases of AP identified in the UK during the study period, 90 cases (96%) were included in the 1-year follow-up. 30 patients (32%) developed further episode(s) of AP. Over one-fifth of patients developed one or more major complication. At initial admission, the most common of these was pancreatic necrosis (n=8, 9%), followed by respiratory failure (n=7, 7%). Reported complications by 1 year were pseudocyst formation (n=9, 10%), diabetes requiring insulin therapy (n=4, 4%) and maldigestion (n=1, 1%). At 1-year postdiagnosis, only 59% of children made a full recovery with no acute or chronic complications or recurrent episodes of AP. Two patients died, indicating a case fatality of ~2.0%.

conclusionsAP in childhood is associated with significant short-term and medium-term complications and comorbidities including risk of recurrence in approximately a third of cases.

Indexed as

Pancreatitis, Acute NecrotizingAcute DiseaseChildHumansMorbidityProspective StudiesEndocrinologyGastroenterology

Identifiers

PMID36053577
PMCPMC9258515
OpenAlexW4284686790

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.