Evidence map›Paper›PMID 36053484›Full record

ArticleJournal of ultrasound2023

Use of 3D ultrasound to characterise temporal changes in thyroid nodules: an in vitro study.

Aldred Cheng, James Wai Kit Lee, Kee Yuan Ngiam

Abstract read
In one paragraph

Article in Journal of ultrasound, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aldred ChengYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
James Wai Kit LeeDivision of Endocrine Surgery, University Surgical Cluster, National University Hospital, Singapore, Singapore.
Kee Yuan NgiamYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. kee_yuan_ngiam@nuhs.edu.sg.ORCID http://orcid.org/0000-0001-5676-2520

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThyroid nodules are extremely common, with prevalence rate up to 68%, yet only 7-15% of these are malignant. Many nodules require surveillance and 2-dimensional ultrasound (2D US) is used. Issues include the huge workload of obtaining and labeling images and difficulty comparing sizes of nodules over time due to large inter-operator variability. Inaccuracies may result in unnecessary FNAC or missed diagnosis of malignant nodules.

methodsWe compared two techniques: freehand plain 2D US against freehand 2D US with gyroscopic guidance, both followed by 3D reconstruction using software. We measured the volume of nodules and a normal thyroid gland.

resultsWe found 2D US with gyroscopic guidance to be superior to plain 2D US as 3D reconstructions of greater accuracy are produced. The volume of the thyroid lobe measured 8.42 cm

conclusionWe find 3D US promising for evaluating size of thyroid nodules, with potential to study other TIRAD characteristics. Freehand 2D US with gyroscopic guidance shows the most promise for producing reliable, accurate and faster 3D reconstructions of thyroid nodules.

Indexed as

Thyroid NoduleHumansSoftwareUltrasonography3D ultrasoundNodule monitoringThyroidThyroid nodulesThyroid volume measurement

Identifiers

PMID36053484
PMCPMC10468465

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.