Evidence map›Paper›PMID 36053437›Full record

ArticleMolecular neurobiology2022

Hydrogen Sulfide Attenuates High-Fat Diet-Induced Obesity: Involvement of mTOR/IKK/NF-κB Signaling Pathway.

Maofang Zhao, Yuan Cheng, Xiaoxuan Wang, Xiaoying Cui, Xiaojing Cheng, Qian Fu, Yilin Song, Peiquan Yu, Yi Liu, Yinghua Yu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Establishment of a Seven-Gene Signature Associated with CD8International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Maofang ZhaoJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Yuan ChengJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Xiaoxuan WangJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Xiaoying CuiQueensland Centre for Mental Health Research, Wacol, QLD, Australia.
Xiaojing ChengJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Qian FuJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Yilin SongJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Peiquan YuJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Yi LiuJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China. cbpeliuyinew@163.com.ORCID http://orcid.org/0000-0001-6176-4977
Yinghua YuJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, China.
Xuzhou Medical College · CNThe University of Queensland · AU

Funding

the Open Research Project of Jiangsu Key Laboratory of Brain Disease Bioinformation JSBL201802the Open Research Project of Jiangsu Key Laboratory of Immunity and Metabolism JSKIM201802the Science and Technology Planning Project of Xuzhou KC20168
6 · The paper itself

Abstract

Obesity has become a public health epidemic worldwide and is associated with many diseases with high mortality including hypertension, diabetes, and heart disease. High-fat diet (HFD)-induced energy imbalance is one of the primary causes of obesity, but the underlying mechanisms are not fully elucidated. Our study showed that HFD reduced the level of hydrogen sulfide (H

Indexed as

Hydrogen SulfideNF-kappa BAnimalsCystathionine beta-SynthaseCytokinesDiet, High-FatInflammationInterleukin-6MiceObesitySignal TransductionTOR Serine-Threonine KinasesTumor Necrosis Factor-alphaCystathionine beta-SynthaseCytokinesHydrogen SulfideInterleukin-6NF-kappa BTOR Serine-Threonine KinasesTumor Necrosis Factor-alphaHydrogen sulfideHypothalamic inflammationmTORNF-κBObesity

Identifiers

PMID36053437
OpenAlexW4294191260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.