Evidence map›Paper›PMID 36053432›Full record

ArticleMagma (New York, N.Y.)2023

Awais A Bajwa, Andreas Neubauer, Michael Schwerter, Lothar Schilling

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Awais A Bajwa *Division of Neurosurgical Research, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Andreas Neubauer *Department of Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Michael SchwerterDepartment of Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Lothar SchillingDivision of Neurosurgical Research, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. lothar.schilling@medma.uni-heidelberg.de.ORCID http://orcid.org/0000-0003-1045-7672
Heidelberg University · DEForschungszentrum Jülich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIt is well known that the use of shift reagents (SRs) in nuclear magnetic resonance (NMR) studies is substantially limited by an intact blood-brain barrier (BBB). The current study aims to develop a method enabling chemical shift imaging in the living rat brain under physiological conditions using an SR, Tm[DOTP] MATERIALS AND

methodsHyperosmotic mannitol bolus injection followed by 60 min infusion of a Tm[DOTP]

resultsBased on the T-XRF measurements, the thulium concentration was estimated at 2.3 ± 1.8 mM in the brain interstitial space. Spectroscopic imaging showed a split of the

conclusionOur novel protocol showed bulk accumulation of Tm[DOTP]

Indexed as

Magnetic Resonance ImagingThuliumAnimalsBrainMagnetic Resonance SpectroscopyOxazolesPyrimidinonesRatsSodium2,3-dihydro-5H-oxazolo(3,2-a)thieno(3,2-d)pyrimidin-5-oneOxazolesPyrimidinonesSodiumThuliumBlood–brain barrierChemical shift reagentMagnetic resonance spectroscopyRatsSodium

Identifiers

PMID36053432
PMCPMC9992022
OpenAlexW4294266827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.