ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2022
Seasonal immune rhythm of leukocytes in the freshwater snakehead fish, Channa punctatus.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Annual rhythm in immune functions of blood leucocytes in an ophidian, Natrix piscator.Scientific reports · 2024Article
- Season affects the estrogen system and the immune response of common carp.Fish physiology and biochemistry · 2024Article
- Automated Hematological Approach and Protein Electrophoretic Pattern in Tilapia (Animals : an open access journal from MDPI · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
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Abstract
Annual rhythms are observed in many physiological processes and are an important approach to cope with seasonal stressors. The use of lower vertebrates as an experimental model is crucial to understand the evolution of this biological clock. This study aims to characterize the seasonal variability in the leukocyte immune responses in Channa punctatus. Leukocytes were harvested from peripheral blood and respiratory burst activity, leukocyte phagocytosis, and nitrite production were assessed to study innate immunity. Peripheral blood lymphocytes were segregated by centrifugation (density gradient) and proliferative responses of lymphocytes, in the presence of mitogens, were used to study cell-mediated immunity. Annual rhythms were validated in superoxide anion production, nitrite release and phagocytosis. Cosinor analysis revealed a differential pattern of lymphocyte proliferation which was dependent upon season and mitogen used. It was concluded that seasonal variation in immune activity might be associated with annual adaptation against diseases and the optimum immune status of seasonal breeders like fish helps them fight seasonal changes.
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Registered trials
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