ArticleAnnals of medicine2022
Association between dyslipidaemia and the risk of hyperuricaemia: a six-year longitudinal cohort study of elderly individuals in China.
Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Associations between cholesterol, high-density lipoprotein, and glucose index and hyperuricemia in patients with diabetes.BMC endocrine disorders · 2026Article
- Lipoprotein combined index and prevalent hyperuricemia among normolipidemic oilfield workers: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Article
- Pear-shaped body types linked to lower risk of gout: genetic evidence from Mendelian randomization.International journal of obesity (2005) · 2025Article
- The dose-response relationship and gender differences of serum uric acid with total cholesterol: a cross-sectional study.The Journal of international medical research · 2025Article
- Sex-specific associations between blood urea nitrogen and risk of hyperuricemia in U.S. adults: the NHANES 1999-2020.Frontiers in endocrinology · 2025Article
- The association between the cardiometabolic index and hyperuricemia: 2011-2016 NHANES.Frontiers in endocrinology · 2025Article
- Nonlinear association of cardiometabolic index with hyperuricemia: insights from the NHANES 1999-2018 study.Frontiers in endocrinology · 2025Article
- Exploring the associations and potential mediators between lipid biomarkers and the risk of developing gout: NHANES 2007-2018.Lipids in health and disease · 2024Article
- The Association of Dietary Diversity with Hyperuricemia among Community Inhabitants in Shanghai, China: A Prospective Research.Nutrients · 2024Article
- Elevated blood pressure and hyperuricemia risk: a retrospective cohort study from Wuhu, China.Scientific reports · 2024Article
- Unraveling the link between hypertriglyceridemia, dampness syndrome, and chronic diseases: A comprehensive observational study.Medicine · 2024Observational
- Associations of Plasma Lipidomic Profiles with Uric Acid and Hyperuricemia Risk in Middle-Aged and Elderly Chinese.Phenomics (Cham, Switzerland) · 2024Article
- Associations of fasting plasma glucose with all-cause mortality and cardiovascular events in older Chinese diabetes patients: A population-based cohort study.Journal of diabetes investigation · 2024Article
- The relationship between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and hyperuricaemia.Lipids in health and disease · 2024Article
- Gender-Specific Differences in Prevalence and Association of Cardio-Metabolic Parameters and Hyperuricemia: A Population-Based Cross-Sectional Study, Nakhon Nayok, Thailand.Iranian journal of public health · 2024Article
- An artificial neural network model for evaluating the risk of hyperuricaemia in type 2 diabetes mellitus.Scientific reports · 2024Article
- Establishment and evaluation of a nomogram prediction model for the risk of vascular calcification in stage 5 chronic kidney disease patients.Scientific reports · 2024Article
- Exploring the Relationship Between Different Obesity Metabolism Indices and Hyperuricemia in Patients with Hypertension and Coronary Heart Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Exploring the Multifaceted Nexus of Uric Acid and Health: A Review of Recent Studies on Diverse Diseases.Biomolecules · 2023Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite abundant evidence linking dyslipidaemia to an increased risk of hyperuricaemia, the exact association between each component of dyslipidaemia and hyperuricaemia remains controversial. Thus, the objective of this research was to examine the correlation between dyslipidaemia and its components, as well as hyperuricaemia in Chinese people over the age of 60.
methodsIn this study, 4018 participants over 60 years without hyperuricaemia were investigated from 2014 to 2020. The association between each dyslipidaemia component and hyperuricaemia was evaluated employing Cox proportional hazards models. This research conducted further stratified and sensitivity analyses to assess the potential relationship.
resultsA total of 1155 participants suffered from hyperuricaemia (28.75%) at the time of the 6-year follow-up survey. In multivariable-adjusted analyses, compared to participants with normal lipid levels, those with dyslipidaemia had 1.28 times the risk (95% confidence interval 1.12 to 1.47) of experiencing hyperuricaemia. The hazard ratios (HR) (95% CI) comparing high TC, high TG, high LDL-C, and low HDL-C of dyslipidaemia with the regular group were 0.99 (0.72 to 1.37), 1.30 (1.07 to 1.57), 1.02 (0.70 to 1.50), and 1.20 (1.00 to 1.44), respectively. There was a nonlinear dose-response between TG, HDL-C, and serum uric acid (SUA).
conclusionsDyslipidaemia and its two distinct types, high TG and low HDL-C, increased hyperuricaemia incidence in this prospective cohort. Further research should be undertaken to investigate the possible reverse causality between different components of dyslipidaemia and hyperuricaemia.
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