ArticleeLife2022
Brain atlas for glycoprotein hormone receptors at single-transcript level.
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Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
What it found
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Who cites it
24 citing papers in PubMed, 26 citations in OpenAlex.
- Is Follicle-Stimulating Hormone (FSH) Misnamed? Rethinking Its Role in Menopause as a Systemic Regulator of Bone, Brain, Metabolism, and Aging.Journal of clinical medicine · 2026Review
- The extragonadal biology of gonadotropin hormones: should we rename these?Endocrine connections · 2026Article
- Conditional replacement of the mouse luteinizing hormone receptor with green fluorescent protein, enabling imaging of cell migration during ovulation.Endocrinology · 2026Article
- Conditional replacement of the mouse LH receptor with GFP, enabling imaging of cell migration during ovulation.bioRxiv : the preprint server for biology · 2026Article
- Neuroendocrine and neural control of bone mass in health and disease.The Journal of clinical investigation · 2026Review
- Gendering the Menstrual Cycle in Behavioral Neuroendocrinology.American journal of human biology : the official journal of the Human Biology Council · 2026Review
- Gonadotropins Across the Lifespan: Their role in the Neurodevelopment-Neurodegeneration Continuum.The Yale journal of biology and medicine · 2026Review
- Article
- The dual face of human chorionic gonadotropin in the CNS: neuroprotection, signaling, and possible pathological effects.Archives of gynecology and obstetrics · 2026Review
- Targeting FSH for osteoporosis, obesity, and Alzheimer's disease.Trends in molecular medicine · 2025Review
- The Hypothalamic-Pituitary-Ovarian Axis, Ovarian Disorders, and Brain Aging.Endocrinology · 2025Review
- Vernal growth of vocal control nucleus Area X, but not HVC, precedes gonadal recrudescence in wild black-capped chickadees (Poecile atricapillus).Journal of neuroendocrinology · 2025Article
- Follicle-stimulating hormone: More than a marker for menopause: FSH as a frontier for women's mental health.Psychiatry research · 2025Review
- Expression of Follicle-Stimulating Hormone Receptor in Von Hippel-Lindau Associated Tumors and Cysts: An Immunohistochemical Study.Journal of kidney cancer and VHL · 2025Article
- Neuroendocrinology of bone.Pituitary · 2024Review
- FSH, bone, belly and brain.The Journal of endocrinology · 2024Review
- Gene-Dose-Dependent Reduction Fshr Expression Improves Spatial Memory Deficits in Alzheimer's Mice.Research square · 2024Article
- The influence of extended fasting on thyroid hormone: local and differentiated regulatory mechanisms.Frontiers in endocrinology · 2024Review
- TSH enhances neurite outgrowth.Frontiers in endocrinology · 2024Article
- Pituitary crosstalk with bone, adipose tissue and brain.Nature reviews. Endocrinology · 2023Review
Corrections and comments
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Authors and funding
26 authors at 5 institutions in 2 countries.
Vitaly RyuCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID 0000-0001-8068-4577
Anisa GumerovaCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Funda KorkmazCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Seong Su KangDepartment of Pathology, Emory University School of Medicine, Atlanta, United States.ORCID 0000-0002-2517-9962
Pavel KatselDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID 0000-0001-8076-0162
Sari MiyashitaCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Hasni KannangaraCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Liam CullenCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Pokman ChanAlamak Biosciences, Beverly, United States.
TanChun KuoCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID 0000-0001-5301-755X
Ashley PadillaCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Farhath SultanaCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Soleil A WizmanCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Natan KramskiyCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Samir ZaidiMemorial Sloan Kettering Cancer Center, New York, United States.
Se-Min KimCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Maria I NewDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, United States.
Clifford J RosenMaine Medical Center Research Institute, Scarborough, United States.
Ki A GoosensCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID 0000-0002-5246-2261
Tal FrolingerCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Vahram HaroutunianDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States.
Keqiang YeFaculty of Life and Health Sciences, and Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced technology, Chinese Academy of Sciences, Shenzhen, China.
Daria LiznevaCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Terry F DaviesCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Tony YuenCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.
Mone ZaidiCenter for Translational Medicine and Pharmacology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID 0000-0001-5911-9522
Icahn School of Medicine at Mount Sinai · USChinese Academy of Sciences · CNEmory University · USMaine Medical Center Research Institute · USMemorial Sloan Kettering Cancer Center · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MResearch Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Carolyn Wei Zhu · 2020 to 2026
$31.0MTargeting FSH for the Therapy of Osteoporosis, Obesity and NeurodegenerationU19AG060917 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLIFFORD JAMES ROSEN, Mone Zaidi · 2019 to 2026
$29.0MThe role of night shift work in metabolic disorders during and after pregnancyP20GM121301 · NIGMS · MAINEHEALTH · PI CLIFFORD JAMES ROSEN · 2017 to 2026
$25.1MInterdisciplinary Study of Marrow Adiposity, Mineral Metabolism & Energy BalanceR24DK092759 · NIDDK · MAINEHEALTH · PI HOROWITZ, MARK C, MACDOUGALD, ORMOND A · 2011 to 2019
$13.0MA Humanized Monoclonal FSH Blocking Antibody for Alzheimer's DiseaseU01AG073148 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Tony Yuen, Mone Zaidi · 2021 to 2026
$10.6MElevated FSH - A Driver for Sex Differences in Alzheimer's DiseaseR01AG074092 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HAROUTUNIAN, VAHRAM, YUEN, TONY · 2021 to 2025
$6.3MProof-of-Concept and Mechanistic Studies to Repurpose Erectile Dysfunction Drugs for Elderly FemalesR01AG071870 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KIM, SE-MIN, YUEN, TONY · 2021 to 2025
$3.9MThyrotropin Receptor, Thyrotropin and Mechanisms of Bone LossR01DK113627 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DAVIES, TERRY FRANCIS, IQBAL, JAMEEL Z · 2017 to 2020
$2.8MMechanisms by which adipocytes adapt to cool environmental temperaturesR01DK121759 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MACDOUGALD, ORMOND A · 2020 to 2024
$2.0MNCI NIH HHS P30 CA008748NIA NIH HHS P30 AG066514NIA NIH HHS R01 AG071870NIA NIH HHS R01 AG074092NIA NIH HHS U01 AG073148NIA NIH HHS U19 AG060917NIDDK NIH HHS R01 DK113627NIDDK NIH HHS R01 DK121759NIDDK NIH HHS R24 DK092759NIGMS NIH HHS P20 GM121301
Abstract
There is increasing evidence that anterior pituitary hormones, traditionally thought to have unitary functions in regulating single endocrine targets, act on multiple somatic tissues, such as bone, fat, and liver. There is also emerging evidence for anterior pituitary hormone action on brain receptors in mediating central neural and peripheral somatic functions. Here, we have created the most comprehensive neuroanatomical atlas on the expression of TSHR, LHCGR, and FSHR. We have used RNAscope, a technology that allows the detection of mRNA at single-transcript level, together with protein level validation, to document
Indexed as
GlycoproteinsSertoli CellsAnimalsBrainHormonesHumansMaleMiceTestisGlycoproteinsHormonesexpression profilingfollicle-stimulating hormonegonadotropin receptorsluteinizing hormonemedicinemousethyroid-stimulating hormone
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.