Evidence map›Paper›PMID 36052991›Full record

ArticleeLife2022

Hemocyte differentiation to the megacyte lineage enhances mosquito immunity against

Ana Beatriz F Barletta, Banhisikha Saha, Nathanie Trisnadi, Octavio A C Talyuli, Gianmarco Raddi, Carolina Barillas-Mury

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Single-cell insights: Mosquito Toll activation enhances granulocyte differentiation and immune surveillance via Notch suppression.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Distinct roles of theCurrent research in insect science · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Exploring new dimensions of immune cell biology inbioRxiv : the preprint server for biology · 2024
    Article
  14. Human Defensin 5 InhibitsTropical medicine and infectious disease · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Microbiota in disease-transmitting vectors.Nature reviews. Microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ana Beatriz F BarlettaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, United States.ORCID 0000-0001-9913-3775
Banhisikha SahaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, United States.
Nathanie TrisnadiLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, United States.
Octavio A C TalyuliLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, United States.ORCID 0000-0002-7026-463X
Gianmarco RaddiLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, United States.ORCID 0000-0003-1056-5403
Carolina Barillas-MuryLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, United States.ORCID 0000-0002-4039-6199
National Institutes of Health · USUniversidade Federal do Rio de Janeiro · BR

Funding

Mosquito Midgut Immune Responses &Malaria TransmissionZ01AI000947 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI BARILLAS-MURY, CAROLINA · 2004 to 2008
$1.8M
Intramural NIH HHS Z01 AI000947
6 · The paper itself

Abstract

Activation of

Indexed as

AnophelesMalariaPlasmodiumAnimalsHemocytesHumansPlasticsPlasticsAnopheles gambiaeantiplasmodial immunityhemocytesinfectious diseasemegacytemicrobiologymosquitoToll pathway

Identifiers

PMID36052991
PMCPMC9545522
OpenAlexW4294287385

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.