ArticleESC heart failure2022
Prevalence and predictors of sleep-disordered breathing in chronic heart failure: the SchlaHF-XT registry.
Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Sleep Disorder Phenotypes and the Risk of Incident Heart Failure:Saudi medical journal · 2026Pooled it
- Hypoxaemic burden in heart failure patients receiving adaptive servo-ventilation.ESC heart failure · 2023Trial
- Evolving Heart Failure Profiles in Quebec from 1998-2021: Insights from the Vision C+ Database.CJC open · 2026Article
- The Intersection of Cardiology and Sleep Medicine: Impact of Sleep-Disordered Breathing on Heart Failure Outcomes.Journal of clinical medicine · 2026Review
- The clinical pathophysiology of atrial fibrillation: outstanding questions from bedside to bench and back.Physiological reviews · 2026Review
- Sleep-disordered breathing in patients with heart failure with preserved left ventricular ejection fraction.Sleep & breathing = Schlaf & Atmung · 2026Article
- [Central sleep apnea: cessation of central respiration control while we sleep : Suggestions for daily practice in diagnosis and therapy].Innere Medizin (Heidelberg, Germany) · 2025Article
- Prognostic value of hypoxaemic burden from overnight oximetry in heart failure with preserved ejection fraction.ESC heart failure · 2025Article
- MyocardialAntioxidants (Basel, Switzerland) · 2025Article
- Obesity and Its Comorbidities: Current Treatment Options, Emerging Biological Mechanisms, Future Perspectives and Challenges.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- Positive Airway Pressure Therapies for Heart Failure: What Do the Trials Tell Us?Cardiac failure review · 2025Review
- Design and Validation of Sleep Apnea Risk Assessment (SARA): A Screening Tool for Moderate-to-Severe Obstructive Sleep Apnea.Nature and science of sleep · 2025Article
- Breathless Nights and Cardiac Frights-How Snoring Is Breaking Hearts.Biomedicines · 2024Article
- The Role of Sleep in Cardiovascular Disease.Current atherosclerosis reports · 2024Review
- Influence of Obstructive Apnea Index on Persistent Left Ventricular Dysfunction in Patients with ST-Segment Elevation Myocardial Infarction.Journal of clinical medicine · 2024Article
- Central sleep apnoea: not just one phenotype.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Clinical and PSG Characteristics Comparison of Central Sleep Apnea in the Elderly and Non-Elderly Patients.Nature and science of sleep · 2024Article
- A call for precision medicine: Facing the challenge of sleep-disordered breathing in heart failure.Sleep medicine · 2023Article
- Insights into the Interaction of Heart Failure with Preserved Ejection Fraction and Sleep-Disordered Breathing.Biomedicines · 2023Review
- Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsHeart failure with preserved ejection fraction (HFpEF) is a condition with increasing prevalence. Sleep-disordered breathing (SDB) is an important co-morbidity in HFpEF. The SchlaHF-XT registry evaluated the sex-specific prevalence and predictors of SDB, including obstructive (OSA) and central sleep apnoea, in patients with HFpEF compared with heart failure with mildly reduced (HFmrEF) or reduced (HFrEF) ejection fraction. METHODS AND
resultsConsecutive adults with chronic heart failure treated according to current guidelines were enrolled. The presence of moderate-to-severe SDB (apnoea-hypopnoea index ≥15/h) was determined using Type 3 polygraphic devices. Of 3289 patients included, 2032 had HFpEF, 559 had HFmrEF, and 698 had HFrEF, of whom 34, 21, 23, and 42%, respectively, were female. Prevalence of SDB in HFpEF was high, but significantly lower than in HFmrEF or HFrEF (36% vs. 41 and 48%, respectively). Rates of SDB in males and females were 41 and 28% in HFpEF, 44 and 30% in HFmrEF, and 50 and 40% in HFrEF. The proportion of males and females with SDB who had OSA was significantly greater in those with HFpEF vs. HFrEF. Male sex, older age, higher body mass index, and New York Heart Association functional Class III/IV were significant predictors of moderate-to-severe SDB in HFpEF patients.
conclusionsPrevalence of SDB in HFpEF was high, but lower than in patients with HFmrEF or HFrEF. Moderate-to-severe SDB occurred more frequently in males than in females across the whole spectrum of heart failure. In both sexes, the proportion of OSA in SDB patients with HFpEF was higher than in those with HFrEF.
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Registered trials
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