Evidence map›Paper›PMID 36052278›Full record

ArticleJournal of immunology research2022

HBV Infection-Related

Xin Chen, Xiaodong Wang, Feng Zhu, Chao Qian, Fanggui Xu, Xin Huang, Wenjie Zhang, Beicheng Sun

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xin ChenDepartment of Hepatobilliary Surgery of Drum Tower Clinical Medical College, Nanjing Medical University, Nanjing, 210008 Jiangsu Province, China.ORCID https://orcid.org/0000-0002-7362-2228
Xiaodong WangDepartment of General Surgery, Northern Jiangsu People's Hospital, Yangzhou, 225001 Jiangsu Province, China.ORCID https://orcid.org/0000-0002-8132-8109
Feng ZhuDepartment of General Surgery, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211100 Jiangsu Province, China.ORCID https://orcid.org/0000-0002-9219-605X
Chao QianDepartment of General Surgery, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211100 Jiangsu Province, China.ORCID https://orcid.org/0000-0002-5869-9227
Fanggui XuDepartment of General Surgery, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211100 Jiangsu Province, China.ORCID https://orcid.org/0000-0003-0248-0100
Xin HuangDepartment of General Surgery, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211100 Jiangsu Province, China.ORCID https://orcid.org/0000-0001-9980-3716
Wenjie ZhangDepartment of Hepatobilliary Surgery of Drum Tower Clinical Medical College, Nanjing Medical University, Nanjing, 210008 Jiangsu Province, China.ORCID https://orcid.org/0000-0002-2730-7577
Beicheng SunDepartment of Hepatobilliary Surgery of Drum Tower Clinical Medical College, Nanjing Medical University, Nanjing, 210008 Jiangsu Province, China.ORCID https://orcid.org/0000-0001-7696-703X
Nanjing Medical University · CNNanjing University of Chinese Medicine · CNNorthern Jiangsu People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methods: We compared differentially expressed genes (DGEs) in HBV-positive and -negative tumor samples and conducted a Spearman correlation study between the DGEs and HBV titers within The Cancer Genome Atlas (TCGA). Moreover, we validated the results of our in-house samples. Results: In this study, we discovered a series of genes that correlated statistically with HBV infection based on the TCGA database. These genes were related to increased inflammation and some oncogenic signaling pathways via Gene Set Enrichment Analysis (GSEA). Conclusions:

Indexed as

Carcinoma, HepatocellularHepatitis BLiver NeoplasmsMembrane ProteinsCarcinogenesisFatty AcidsHepatitis B virusHumansImmunosuppression TherapyPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktFatty AcidsMembrane ProteinsPDZK1 protein, humanPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akt

Identifiers

PMID36052278
PMCPMC9427290
OpenAlexW4293023521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.