Evidence map›Paper›PMID 36052046›Full record

ReviewComputational intelligence and neuroscience2022

Preemptive Diagnosis of Alzheimer's Disease in the Eastern Province of Saudi Arabia Using Computational Intelligence Techniques.

Sunday O Olatunji, Aisha Alansari, Heba Alkhorasani, Meelaf Alsubaii, Rasha Sakloua, Reem Alzahrani, Yasmeen Alsaleem, Reem Alassaf, Mehwash Farooqui, Mohammed Imran Basheer Ahmed and 1 more

Abstract readReview
In one paragraph

Review in Computational intelligence and neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sunday O OlatunjiCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID https://orcid.org/0000-0003-2993-7641
Aisha AlansariCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID https://orcid.org/0000-0002-4600-976X
Heba AlkhorasaniCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Meelaf AlsubaiiCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Rasha SaklouaCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Reem AlzahraniCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID https://orcid.org/0000-0003-3502-1541
Yasmeen AlsaleemCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Reem AlassafCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID https://orcid.org/0000-0001-5563-528X
Mehwash FarooquiCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID https://orcid.org/0000-0002-3887-3638
Mohammed Imran Basheer AhmedCollege of Computer Science and Information Technology, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Jamal AlhiyafiDepartment of Computer Science, Kettering University, Flint, Michigan 48504, USA.ORCID https://orcid.org/0000-0003-3616-6531

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's Disease (AD) is a silent disease that causes the brain cells to die progressively, influencing consciousness, behavior, planning ability, and language to name a few. AD increases exponentially with aging, where it doubles every 5-6 years, causing profound implications, such as swallowing difficulties and losing the ability to speak before death. According to the Ministry of Health in Saudi Arabia, AD patients will triple by 2060 to reach 14 million patients worldwide. The rapid rise of patients is caused by the silent progress of the disease, leading to late diagnosis as the symptoms will not be distinguished from normal aging affect. Moreover, with the current medical capabilities, it is impossible to confirm AD with 100% certainty via specific medical examinations. The literature review revealed that most recent publications used images to diagnose AD, which is insufficient for local hospitals with limited imaging capabilities. Other studies that used clinical and demographical data failed to achieve adequate results. Consequently, this study aims to preemptively predict AD in Saudi Arabia by employing machine learning (ML) techniques. The dataset was acquired from King Fahad Specialist Hospital (KFSH) in Dammam, Saudi Arabia, containing standard clinical tests for 152 patients. Four ML algorithms, namely, support vector machine (SVM), k-nearest neighbors (k-NN), Adaptive Boosting (AdaBoost), and eXtreme Gradient Boosting (XGBoost), were employed to preemptively diagnose the disease. The empirical results demonstrated the robustness of SVM in the pre-emptive diagnosis of AD with accuracy, precision, recall, and area under the receiver operating characteristics (AUROC) of 95.56%, 94.70%, 97.78%, and 0.97, respectively, with 13 features after applying the sequential forward feature selection technique. This model can assist the medical staff in controlling the progression of the disease at low costs.

Indexed as

Alzheimer DiseaseBrainHumansMachine LearningSaudi ArabiaSupport Vector Machine

Identifiers

PMID36052046
PMCPMC9427223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.