Evidence map›Paper›PMID 36051841›Full record

ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2022

Efficacy and safety of drug-coated balloons according to coronary vessel size. A report from the BASKET-SMALL 2 trial.

Ahmed Farah, Mohamed Elgarhy, Marc-Alexander Ohlow, Jochen Wohrle, Norman Mangner, Sven Möbius-Winkler, Marco Cattaneo, Nicole Gilgen, Bruno Scheller, Raban Jeger

Open access · goldAbstract read
In one paragraph

Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Ahmed FarahKnappschaftskrankenhaus, Westfalen-Clinic, Dortmund, Germany.
Mohamed ElgarhyCentral Hospital, Bad Berka, Germany.
Marc-Alexander OhlowSRH, Wald-Clinic, Gera, Germany.
Jochen WohrleMedical Campus Lake Constance, Friedrichshafen, Germany.
Norman MangnerHerzzentrum Dresden, Technische Universität Dresden, Dresden, Germany.
Sven Möbius-WinklerUniversity Hospital Jena, Jena, Germany.
Marco CattaneoUniversity Hospital Basel, University of Basel, Basel, Switzerland.
Nicole GilgenUniversity Hospital Basel, University of Basel, Basel, Switzerland.
Bruno SchellerUniversity Hospital Saarland, Homburg, Germany.
Raban JegerUniversity Hospital Basel, University of Basel, Basel, Switzerland.
Jena University Hospital · DEKlinikum Westfalen (Germany) · DESaarland University · DESRH Wald-Klinikum Gera · DETriemli Hospital · CHTU Dresden · DEUniversity Hospital of Basel · CHUniversity of Basel · CHZentralklinik Bad Berka · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In BASKET-SMALL 2, drug-coated balloons (DCB) were non-inferior to drug-eluting stents (DES) in de-novo stenosis of small coronary vessels (≤ 2.75 mm) regarding clinical endpoints up to 36 months. Aim: In the present subgroup analysis, we aimed to analyze the effect of the two treatment strategies in different vessel sizes. Material and methods: Patients were analyzed according to the size of the device used (small > 2.5 mm vs. very small ≤ 2.5 mm). The primary endpoint was major adverse cardiac events (MACE), while secondary endpoints were target vessel revascularization (TVR), non-fatal myocardial infarction, cardiac death, and all-cause mortality, all at 36 months. Interactions for the different groups were assessed with Cox regression analysis. Results: Overall, 758 patients were enrolled in this analysis, of which 437 (58%) had very small vessel disease. There were similar results in both treatment groups for the primary endpoint in both small and very small vessels (DCB vs DES, MACE at 3 years in small vessels HR = 1.31, 95% CI: 0.74-2.32, Conclusions: Efficacy and safety of DCB are similar irrespective of vessel size. However, there is a beneficial effect of DCB over paclitaxel-eluting stents regarding TVR, non-fatal myocardial infarction and MACE that is most pronounced in very small coronary arteries.

Indexed as

drug-coated balloondrug-eluting stentpaclitaxelsmall vessel diseasevessel size

Identifiers

PMID36051841
PMCPMC9421526
OpenAlexW4292552864

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.