Evidence map›Paper›PMID 36051724›Full record

ArticleCureus2022

SARS-CoV-2 Seroprevalence in Delhi, India, During September-October 2021: A Population-Based Seroepidemiological Study.

Pragya Sharma, Saurav Basu, Suruchi Mishra, Ekta Gupta, Reshu Agarwal, Pratibha Kale, Nutan Mundeja, B S Charan, Gautam Singh, Mongjam Singh

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Dynamics of SARS-CoV-2 seroassay sensitivity: a systematic review and modelling study.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Effect of Vaccination on Seroprevalence of COVID-19 among Blood donors - A cross-sectional Analytic Study from South India.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Pragya SharmaCommunity Medicine, Maulana Azad Medical College, New Delhi, IND.
Saurav BasuEpidemiology and Public Health, Indian Institute of Public Health, Public Health Foundation of India, New Delhi, IND.
Suruchi MishraCommunity Medicine, Vardhaman, New Delhi, IND.
Ekta GuptaVirology, Institute of Liver and Biliary Sciences, New Delhi, IND.
Reshu AgarwalVirology, Institute of Liver and Biliary Sciences, New Delhi, IND.
Pratibha KaleMicrobiology, Institute of Liver and Biliary Sciences, New Delhi, IND.
Nutan MundejaHealth Services, Government of National Capital Territory, New Delhi, IND.
B S CharanPreventive Medicine, Directorate General of Health Services, Government of National Capital Territory, Delhi, IND.
Gautam SinghState Surveillance Unit, Directorate General of Health Services, Government of National Capital Territory, Delhi, New Delhi, IND.
Mongjam SinghCommunity Medicine, Maulana Azad Medical College, New Delhi, IND.
Public Health Foundation of India · INGovernment of India · INInstitute of Liver and Biliary Sciences · INDirectorate General of Health Services · BDInstitute of Public Health · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background A previous community-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serosurvey in Delhi in January 2021 reported a seroprevalence of 50.52%. We conducted a repeat serosurvey to obtain a recent estimate of the seroprevalence of IgG SARS-CoV-2 in the general population of Delhi, India. Methods This cross-sectional study was conducted from September 24 to October 14, 2021, in 274 wards of Delhi among 27,811 participants through a multistage sampling technique. Results The crude seroprevalence was 89.5% (95% CI 89.1, 89.8), weight for age and sex was 88% (95% CI 87.6, 88.4), and after adjustment for assay performance was estimated as 97.5% (95% CI 97.0, 98.0). On adjusted analysis, the odds of seroconversion in the participants vaccinated with at least one dose of either COVID-19 vaccine (Covishield/Covaxin) was more than four times compared to the unvaccinated ones (aOR 4.2 (3.8, 4.6)). 86.8% of the seropositive individuals had a SARS-CoV-2 signal/cut-off ≥4.0 although it was significantly lower in the pediatric age group. Post-second wave (August to October 2021), on average there were daily 39 new COVID-19 cases and 0.44 deaths which during Omicron driven the third wave in January to March 2022 increased to daily 4,267 cases and 11.6 deaths. Conclusion A high prevalence of IgG antibodies against SARS-CoV-2 with likely higher antibody titres in the vaccinated compared to the unvaccinated groups with evidence of hybrid immunity in a majority of the population was protective against severe disease during transmission of subsequent omicron variants.

Indexed as

covid-19indiaseroprevalenceserosurveyvaccination

Identifiers

PMID36051724
PMCPMC9420192
OpenAlexW4288716567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.