Evidence map›Paper›PMID 36051605›Full record

ArticleWorld journal of psychiatry2022

Xin-Wei Li, Ming-Yuan Zhang, Zhi-Jun Li, Li-Zhe Ai, Meng-Di Jin, Ning-Ning Jia, Meng-Tong Xie, Yu-Qing Yang, Wei-Zhen Li, Lin Dong and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xin-Wei LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Ming-Yuan ZhangDepartment of Endemic Diseases and Parasitic Diseases Prevention, Yantai Center for Disease Control and Prevention, Yantai 264003, Shandong Province, China.
Zhi-Jun LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Li-Zhe AiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Meng-Di JinDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Ning-Ning JiaDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Meng-Tong XieDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Yu-Qing YangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Wei-Zhen LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Lin DongDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Qiong YuDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China. yuqiong@jlu.edu.cn.
Jilin University · CNInstitute of Endemic Disease Control in Shandong Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSchizophrenia (SCZ) is a complex disease which can be affected by both genetic and environmental factors. Prenatal famine exposure may cause changes in DNA methylation levels of genes. Meanwhile, maternal nutrition during pregnancy is a pivotal environmental factor in the development of SCZ. DNA methylation may be an intermediate factor mediating exposure to famine during pregnancy and SCZ, and DNA methylation quantitative trait loci might serve as a promising tool for linking SCZ and prenatal famine.

aimTo analyze the association between prenatal famine exposure and SCZ risk in Northeast Han Chinese through analysis of DNA methylation related loci.

methodsA total of 954 Han Chinese from Northeast China were recruited, including 443 patients with SCZ and 511 healthy controls. The participants were further divided into famine (born in 1960-1962) and non-famine (born in 1963-1965) groups to investigate the effect of prenatal famine exposure. Four single-nucleotide polymorphisms (SNPs) selected according to the relevant literature were genotyped, namely, rs11917047 in

resultsBased on the sequencing data, genotype distributions and allele frequencies of the four selected SNPs were determined. All genotype frequencies of the four SNPs in the healthy control group were tested for deviation from Hardy-Weinberg equilibrium (

conclusionOur study suggested that rs61955196 in

Indexed as

ABCB9 polymorphismDNA methylationPrenatal faminers61955196Schizophrenia

Identifiers

PMID36051605
PMCPMC9331447
OpenAlexW4285798935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.