Evidence map›Paper›PMID 36051593›Full record

ReviewFrontiers in bioengineering and biotechnology2022

Advances in nanocarriers to improve the stability of dsRNA in the environment.

Wenling Yang, Baitao Wang, Gao Lei, Guocan Chen, Dehai Liu

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  11. Advances in the Control of Plant Fungal Pathogens.Journal of fungi (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenling YangKey Laboratory of Microbial Engineering at the Institute of Biology, Institute of Biology Co., Ltd., Henan Academy of Sciences, Zhengzhou, China.
Baitao WangKey Laboratory of Microbial Engineering at the Institute of Biology, Institute of Biology Co., Ltd., Henan Academy of Sciences, Zhengzhou, China.
Gao LeiKey Laboratory of Microbial Engineering at the Institute of Biology, Institute of Biology Co., Ltd., Henan Academy of Sciences, Zhengzhou, China.
Guocan ChenKey Laboratory of Microbial Engineering at the Institute of Biology, Institute of Biology Co., Ltd., Henan Academy of Sciences, Zhengzhou, China.
Dehai LiuKey Laboratory of Microbial Engineering at the Institute of Biology, Institute of Biology Co., Ltd., Henan Academy of Sciences, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNAi technology, known as a revolutionary technology in the history of pesticides, has been identified as a very promising novel approach for crop protection, which is of great significance for achieving the sustainable agricultural development of the United Nations Food and Agriculture Organization. Although many studies have shown that RNA biopesticides have strong application prospects, its stability seriously restricts the commercial use. As the core component of RNAi, double-stranded RNA (dsRNA) is unstable in its natural form. Therefore, how to ensure the stability of dsRNA is one of the most significant challenges in realizing the commercial use of RNA biopesticides. Nanomaterials such as cationic polymers and lipofectamine can improve the stability of dsRNA in the environment, which has been proved. This paper reviews the recent research progress of nanomaterials that can be used to improve the environmental stability of dsRNA, and discusses the advantages and limitations of different nanomaterials combined with dsRNA, which provides reference for the selection of dsRNA nanoformulations.

Indexed as

dsRNAnanomaterialpest controlRNA biopesticidestability

Identifiers

PMID36051593
PMCPMC9424858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.