ArticleACS sustainable chemistry & engineering2021
Avoiding Regrettable Substitutions: Green Toxicology for Sustainable Chemistry.
Article in ACS sustainable chemistry & engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals.Annals of global health · 2024Pooled it
- Beyond genetics: how environmental stressors drive pediatric hypertension risk.Pediatric nephrology (Berlin, Germany) · 2026Review
- Prevalence and reproductive toxicity of di-2-ethylhexyl terephthalate (DEHTP) and other substituted benzene carboxylic acid derivatives used as phthalate alternatives.Environmental pollution (Barking, Essex : 1987) · 2026Review
- Analyzing the landscape of "clean" products for textured hair at a Los Angeles Target.Journal of exposure science & environmental epidemiology · 2026Article
- Advancing the Discovery of Emerging Contaminants: A Leap in Technology and Data.Environmental science & technology · 2026Review
- Gestational Exposure to 10 Classes of Priority Chemicals and Birth Outcomes in the ECHO Cohort.JAMA network open · 2026Article
- Bridging the life-course exposome approach with a life-cycle perspective in safe and sustainable by design (SSbD) for chemical risk.Human genomics · 2026Article
- USEtox modeling of children's exposures to Bisphenol A (BPA) and alternatives in toys.Journal of exposure science & environmental epidemiology · 2026Article
- A Mechanochemical Kolbe-Schmitt Reaction: Catechol Carboxylation Provides Building Blocks for Renewable Plasticizers.Angewandte Chemie (International ed. in English) · 2026Article
- Placental toxicity of alternative plasticizers: Current knowledge and future directions.Reproductive toxicology (Elmsford, N.Y.) · 2026Review
- Being Concerned with Substances of Concern: A Classification of Ethical Dilemmas in Circular Product Design.Science and engineering ethics · 2026Article
- Insights from Life Cycle Assessment to Inform Chemical Substitution, Alternatives Assessment and Safe and Sustainable-by-Design.Environmental science & technology · 2026Article
- Green toxicology only becomes beautiful through AI.Frontiers in chemistry · 2026Review
- Environmental co-exposure to microplastics and phenol may influence redox signaling and tumor microenvironment dynamics.Journal of Cancer · 2026Review
- Parabens and estrogen-mediated cancers: unraveling coincidence, co-occurrence, and causality.npj women's health · 2026Review
- AI snake oil? A risk/benefit analysis for toxicology.Frontiers in artificial intelligence · 2026Article
- Beyond Estrogenicity: A Comparative Assessment of Bisphenol A and Its Alternatives in In Vitro Assays Questions Safety of Replacements.Environmental science & technology · 2025Article
- Advanced Proteomics Approaches Hold Potential for the Risk Assessment of Metabolism-Disrupting Chemicals as Omics-Based NAM: A Case Study Using the Phthalate Substitute DINCH.Environmental science & technology · 2025Article
- Titania: an integrated tool for in silico molecular property prediction and NAM-based modeling.Molecular diversity · 2025Article
- Mapping the chemical complexity of plastics.Nature · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Green chemistry seeks to design less hazardous chemicals, but many of the efforts to replace chemicals have resulted in so-called "Regrettable Substitutions", when a chemical with an unknown or unforeseen hazard is used to replace a chemical identified as problematic. Here, we discuss the literature on regrettable substitution and focus on an oft-mentioned case, Bisphenol A, which was replaced with Bisphenol S-and the lessons that can be learned from this history. In particular, we focus on how Green Toxicology can offer a way to make better substitutions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.